Learning objectives
To demonstrate the role and value of (18-FDG) PET/CT for accurately differentiating malignant,
benign and help judging equivocal or intermediate Solitary Pulmonary Nodule (SPN),
and further correlation of the (18-FDG) PET/CT scan results with morphological features of CT and histopathological results.
Background
Solitary pulmonary nodules (SPNs) refer to round or oval lung lesions,
with clear margins,
not more than 30 mm in diameter,
surrounded by healthy normal lung parenchyma,
and not associated with satellite lesions,
atelectasis,
pneumonia or hilar enlargement,
neither concurrent mediastinal lymphadenopathy.[1]
Although most SPNs are benign,
about 35% are primary malignancies [2],
with majority of those SPNs are in TNM stage IA,
with a 5-year survival rate for patients of 61% to 75% [3].
Because of the small lesion volume and the lack of...
Findings and procedure details
Methods:
Upon Ethical Committee approval,
the retrospective study was conducted including 24 patients whose chest radiographs showed (SPN)(30 nodules),
including 13 (54%) males,
and 11 (46%) females,
with age ranges from 28 to 79 with the mean age 58.5 years ± 2.31 SD.
No significant age differences in both sexes.
The study took 6 months,
starting from June 2017 to early 2018 in Maadi Military Hospital,
and in a private center in Egypt.
Inclusion criteria were patients of age above 28,
with female patients being...
Conclusion
(18-FDG)PET/CT proves to be excellent for differentiation of SPN,
with excellent sensitivity,
specificity,
PPV and NPV,
with good agreement of results of PET/CT with histopathological samples obtained.
The max.SUV can be roughly an indicator of histological type of lung cancer,
with squamous cell carcinoma was higher than that of the adenocarcinoma,
and that of bronchioloalveolar carcinoma.
It’s recommended using PET/CT in correlation with other factors.
Personal information
Contact:Dr.
Sherif Mohsen Shalaby,
MSc
[email protected]
Diagnostic and Interventional Radiology Registrar,
National Institute of Diabetes and Endocrinology (NIDE),
Dar Al Fouad Hospitals (DAFH),ERMED.
Egypt
Prof.
Dr.
Wael Shawaf,
M.D
Prof.
of Diagnostic and Interventional Radiology,
Maadi Military Hospital,
International Medical Center,
Cairo.
Egypt
References
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571–577,
2008.
Wang L,
Chen Y,
Tang K,
Lin J,
Zhang H. The Value of 18F-FDG PET/CT Mathematical Prediction Model in Diagnosis of Solitary Pulmonary Nodules.
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F. Revisions in the international system for staging lung cancer.
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