Aims and objectives
Development of esophageal varices is the major complication of liver cirrhosis (LC),
bleeding from varices is most serious and life-threatening complication of LC [1-4].
Therefore,
all LC patients should undergo endoscopic screening for varices at diagnosis.
Endoscopic require that patients repeatedly undergo an unpleasant procedure.
However,
endoscopy should be repeated with or without varices at a few years later.
We presented at EPOS (C-1125) of ECR 2018 that the severity of portal hypertension with LC can be estimated by measuring the attenuation value obtained by...
Methods and materials
Patients
This study was approved by the relevant institutional review board,
and the need to obtain informed consent from patients was waived for this retrospective study.
We retrospective selected consecutive 62 patients with LC who were ACE-MDCT and endoscopy for diagnosis of LC from February 2016 to December 2017.
We excluded 35 patients with LC.
These patients had unmeasurable of Child-pugh classification (n = 17),insufficient amount of contrast material dose (n = 5),
post TAE (n = 5),
post hepatectomy (n = 4),
imaging timing...
Results
The attenuation value was correlated withserum albumin levels,
serum total bilirubin level,
prothrombin activity,
fibrosis index based on the four factors and aspartate aminotransferase to platelet ratio index (Table 2).
The attenuation value was indicated the most significant difference in all items (Table 3).
The best cut-off attenuation value for predicting EVs,
according to ROC analysis,
was 13.4HU (sensitivity: 92%,
specificity: 92% and AUC: 0.954 [95% confidence interval: 0.878-1]) (Fig.
2).
Conclusion
The present study indicated correlation between the attenuation value and most biochemical markers related to hepatic function.
Further,
we compare the with EVs to the without EVs in the attenuation value and biochemical markers related to hepatic function,
the attenuation value indicated the most significant differences in the all item.
From the aboves,
we were indicated that the attenuation value was related to hepatic function and was useful for prediction of EVs with LC more than biochemical markers related to hepatic function.
In addition,
we...
Personal information
Yasuhiro Inokuchi,
RT
Department of Radiology,
Edogawa Hospital,
Tokyo,
Japan;
[email protected]
Saki Koya,
RT
Department of Radiology,
Edogawa Hospital,
Tokyo,
Japan.
Masahiro Uematsu,
RT
Department of Radiology,
Edogawa Hospital,
Tokyo,
Japan.
Tsuneyuki Takashina,
MD
Department of Radiology,
Edogawa Hospital,
Tokyo,
Japan.
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