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Clinical Research Progress of Gualou Xiebai Banxia Decoction in the Treatment of Chest Stuffiness

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DOI: 10.23977/medcm.2024.060114 | Downloads: 5 | Views: 150

Author(s)

Panpan He 1, Zhengfang Zhou 1, Peng Lei 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, 712046, China
2 Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China

Corresponding Author

Peng Lei

ABSTRACT

Coronary heart disease (CHD) is a kind of common diseases, and its incidence increases with the change of people's lifestyle. In Jingui Yaolue, Gualou Xiebai Banxia decoction is a commonly used medicine for treating chest pain in clinic. With the rapid development of science and technology and the remarkable improvement of medical level, the pharmacological research, efficacy exploration and clinical application of the medicinal components of this prescription are helpful to improve the therapeutic effect of chest stuffiness. The report[1] shows that the incidence and mortality of cardiovascular diseases (CVD) in China are still increasing, and there has not yet been a turning point for the reduction of the burden of disease. At present, stroke, coronary heart disease, and heart failure still account for a large proportion of CVD patients in China. Coronary heart disease (CHD) is short for coronary atherosclerotic heart disease (CHD), which belongs to the category[2] of chest stuffiness in traditional Chinese medicine. Chest stuffiness is a clinical symptom mainly manifested as chest discomfort or pain, and in severe cases, chest and back pain may be felt. It is accompanied by difficulty breathing, and even affect sleep. In mild cases, patients may experience a feeling of tightness or mild discomfort in the chest, while in severe cases, the main manifestation is pain in the chest and back. In the Han Dynasty, Zhang Zhongjing put forward the name of "chest obstruction" for the first time in his Jin-Guiyao Lue (Synopsis of Prescriptions of the Golden Prescriptions), and recorded that Gualou Xiebai Banxia decoction was used to treat chest obstruction, pain, shortness of breath, and pulse syndrome. The composition of the decoction is Gualou, Xiebai, Pinellia, and liquor. 

KEYWORDS

Gualou Xiebai Banxia decoction, Chest stuffiness, Coronary heart disease, Clinical application

CITE THIS PAPER

Panpan He, Zhengfang Zhou, Peng Lei, Clinical Research Progress of Gualou Xiebai Banxia Decoction in the Treatment of Chest Stuffiness. MEDS Chinese Medicine (2024) Vol. 6: 99-105. DOI: http://dx.doi.org/10.23977/medcm.2024.060114.

REFERENCES

[1] Shengshou Hu, Zengwu Wang. Summary of China Cardiovascular Health and disease Report 2022 [J]. China Cardiovascular Research [J], 2023, 21(07):577-600. 
[2] Haijiao Shi, Lili Ding, Yushi Zhou, Mingxue Zhang. Research progress on the pathogenesis of coronary atherosclerotic heart disease combined with stroke [J]. Journal of Chinese medicine, 2022, 40 (12): 146-149. 
[3] Haiyan Yan, Chuncai Zou. Advances in pharmacological effects and mechanisms of Trichosanthis fructula and prospect of network pharmacology [J]. International Journal of Pharmaceutical Research, 2019, 46(02):89-96+115. 
[4] Fan Yang, Xuan Zhang, Huihui Zhang. Exploring the pharmacological effects of the active components of Psidium guajava based on network pharmacology [J]. Chinese Pharmacoeconomics, 2021, 16(09):92-98. 
[5] Rong Wang, Sihui Bai, Lulu Wang. Advances in chemical constituents and pharmacological effects of crostemon bunge [J]. Wild Plant Resources of China, 2021, 40(10):73-82. 
[6] Zijun Jia, Qingbing, Yan Zhang. Mechanism of Trichosanthis fructus-Xiebai drug against atherosclerosis based on network pharmacology and in vitro experiments [J]. Journal of Hunan University of Traditional Chinese Medicine, 2023, 43(11):2061-2070. 
[7] Xiaotong Geng, Qi Liu, Jiaojiao Hua. Advances in chemical constituents and pharmacological effects of Pinellia pinellia [J]. Shanxi Chemical Industry, 2023, 43(09):53-54+61. 
[8] Xiaochong Huang, Wei Yin. Poets in the field of Pinellia sinensis [J]. Zhongnan Pharmacy (YongYao and Kang), 2017(06):7-13. 
[9] Huakang He, Research progress on chemical constituents and pharmacological effects of Pinellia ternata [J]. Collection of Contemporary Medicine, 2020, 18(07):18-20. 
[10] Lan Zhang, Honglei Li. Research progress of Gualou Xiebai Banxia decoction in the treatment of chest arcinoma [J]. China Emergency Medicine of Traditional Chinese Medicine, 2019, 28(09):1689-1692. 
[11] Xiaoli Yan. Study on the clinical effect of modified Gualou Xiebai Banxia decoction on the high-risk population of coronary heart disease (phlegm dampness and blood stasis syndrome) [J]. Changchun University of Traditional Chinese Medicine, 2023. 
[12] Nan Cai, Jing Feng. Relationship between plasma D-dimer level and coronary thrombus burden in elderly patients with acute ST-segment elevation myocardial infarction [J]. Journal of Cardio-Cerebrovascular Disease of Integrated Traditional Chinese and Western Medicine, 2023, 21(22):4188-4193. 
[13] Jing Zhou, Yan Zhang, Qian Zhang. Protective effect of Gualou Xiebai Banxia decoction on myocardial infarction in rats [J]. Liaoning Journal of Traditional Chinese Medicine, 2016, 43(02):410-412+448. 
[14] Xueran Zhang. Effect of Gualou Xiebai Banxia decoction combined with conventional western medicine on patients with acute myocardial infarction [J]. China Minkang Med, 2023, 35(11):111-113. 
[15] Chunxiao Ju, Yao Zhang, Xiaolin Liu. Methodological quality assessment of guidelines and consensus on the prevention and treatment of chronic heart failure [J]. Chinese Journal of Evidence-based Medicine, 2021, 21(09):1091-1097. 
[16] Hui Zhang. Clinical observation of Zhenwu decoction combined with Gualou Xiebai Banxia decoction in the treatment of generalized chronic heart failure with Yang deficiency and water [J]. Modern Distance Education of Chinese traditional Medicine, 2023, 21(16):45-47. 
[17] Yan Xiong. Effect of compound Danshen dripping pills on angina pectoris and cardiac function in patients with unstable angina pectoris [J]. Forum of Primary Medical     Science, 2023, 27(32):124-126. 
[18] Fubao Deng, Junyan Yin, Wanli Gu. Effect of Gualou Xiebai Banxia decoction on unstable angina pectoris [J]. Chinese Health Standard Management, 2023, 14(09):137-140. 
[19] Wei Lu, Wuwang Fang. Meta-analysis of clinical efficacy of Gualou Xiebai decoction in the treatment of unstable angina pectoris [J]. Clinical Research of Chinese Medicine, 2023, 15(05):112-116. 
[20] Yong Li. Comparison of clinical effect of ticagrelor and clopidogrel in the treatment of coronary heart disease with myocardial ischemia [J]. China Practical Medicine, 2012, 17(04):143-145. 
[21] Jianmin Zhang, Xiuming Jin, Shijun Wang et al. Experimental study on treatment of acute myocardial ischemia with Gualou Xiebai Banxia Decoction [J]. Chinese General Medicine, 2004(08):544-545. (in Chinese) 
[22] Ru Jin, Yuguang Wang, Chunmiao Xue et al.  Consensus report on prescription review of proprietary Chinese medicines in primary care in Beijing (2018 edition) [J]. Chinese Journal of Hospital Pharmacy, 2018, 38(18):1877-1887+1892. 
[23] Baohua Zeng, Ting Ouyang. Clinical observation of Gualou Xiebai Banxia decoction in the treatment of coronary heart disease [J]. Guangming Traditional Chinese Medicine, 2022, 37(08):1355-1357. 
[24] Zhengqiang Jiang. Effect of traditional Chinese medicine Guawei-Xiebai Banxia decoction on inhibiting inflammatory response in patients with angina pectoris of coronary atherosclerotic heart disease [J]. Heilongjiang Traditional Chinese Medicine, 2021, 50(06):149-150. 
[25] Yushun Kang. Clinical observation of Gualou Xiebai Banxia decoction combined with nitroglycerin in the treatment of unstable angina pectoris with congestion of phlegm [J]. Modern Distance Education of Chinese traditional Medicine, 2021, 19(17):95-97. 
[26] Hua Qian. Curative effect of Gualou Xiebai Banxia decoction combined with Danshen decoction in the treatment of coronary heart disease and dyslipidemia [J]. Journal of Rational Drug Use in Clinic, 2019, 12(34):12-13.

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