Abstract
In recent years, cannabinoids, particularly cannabidiol (medical marijuana), have attracted considerable attention. This review addresses various aspects including metabolism. Other cannabinols of interest are THC and the hydroxyl quinone metabolite. Physiological influences are addressed, particularly anticancer action, receptors, antioxidants, and neurological effects. A unifying mechanism is invoked based on electron transfer, reactive oxygen species and oxidative stress.
Keywords: Cannabinoids, cannabidiol, metabolism, therapy, toxicity, electron transfer, reactive oxygen species.
The Natural Products Journal
Title:Cannabinoids (CBD, CBDHQ and THC): Metabolism, Physiological Effects, Electron Transfer, Reactive Oxygen Species and Medical Use
Volume: 4 Issue: 1
Author(s): Peter Kovacic and Ratnasamy Somanathan
Affiliation:
Keywords: Cannabinoids, cannabidiol, metabolism, therapy, toxicity, electron transfer, reactive oxygen species.
Abstract: In recent years, cannabinoids, particularly cannabidiol (medical marijuana), have attracted considerable attention. This review addresses various aspects including metabolism. Other cannabinols of interest are THC and the hydroxyl quinone metabolite. Physiological influences are addressed, particularly anticancer action, receptors, antioxidants, and neurological effects. A unifying mechanism is invoked based on electron transfer, reactive oxygen species and oxidative stress.
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Cite this article as:
Kovacic Peter and Somanathan Ratnasamy, Cannabinoids (CBD, CBDHQ and THC): Metabolism, Physiological Effects, Electron Transfer, Reactive Oxygen Species and Medical Use, The Natural Products Journal 2014; 4 (1) . https://dx.doi.org/10.2174/2210315504666140512220028
DOI https://dx.doi.org/10.2174/2210315504666140512220028 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
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Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
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