Abstract
Microfluidic continuous cell separation based on hydrodynamic interaction in a microfluidic channel has attracted attention because of its robustness, high throughput and cell viability. This paper systematically gives an overview on recent advances in hydrodynamic particle and cell separation in microfluidic devices. It presents the basic ideas and fluid mechanics for the hydrodynamic interaction of a particle in a microfluidic system. Secondly, different kinds of devices are introduced with detailed descriptions of their mechanisms, designs and performances. Finally, the review addresses some practical issues of microfluidic sorting devices for use in biological or medical studies.
Micro and Nanosystems
Title: Microfluidic Hydrodynamic Cell Separation: A Review
Volume: 1 Issue: 3
Author(s): Zhigang Wu and Klas Hjort
Affiliation:
Abstract: Microfluidic continuous cell separation based on hydrodynamic interaction in a microfluidic channel has attracted attention because of its robustness, high throughput and cell viability. This paper systematically gives an overview on recent advances in hydrodynamic particle and cell separation in microfluidic devices. It presents the basic ideas and fluid mechanics for the hydrodynamic interaction of a particle in a microfluidic system. Secondly, different kinds of devices are introduced with detailed descriptions of their mechanisms, designs and performances. Finally, the review addresses some practical issues of microfluidic sorting devices for use in biological or medical studies.
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Cite this article as:
Wu Zhigang and Hjort Klas, Microfluidic Hydrodynamic Cell Separation: A Review, Micro and Nanosystems 2009; 1 (3) . https://dx.doi.org/10.2174/1876402910901030181
DOI https://dx.doi.org/10.2174/1876402910901030181 |
Print ISSN 1876-4029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1876-4037 |
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