Abstract
Berberine, a fluorescent, aromatic, heterocyclic alkaloid, produced in a diversity of plants, was found to have curative properties in Chinese herbal medicine. Berberine is used as a treatment for gastric and inflammatory diseases and as an antimicrobial agent. More recently the potential of this alkaloid in diverse new medical application like cardiology, neurology and oncology is being investigated. As a result of its fluorescent properties, it has also been used in chemistry to study protein conformation and protein/protein interactions and to quantitate non-fluorescent compounds. All these applications will be summarized and discussed in this review.
Keywords: Berberine, fluorescent, alkaloid, analysis, medicine, biochemistry
Mini-Reviews in Organic Chemistry
Title: Berberine: A Fluorescent Alkaloid with a Variety of Applications from Medicine to Chemistry
Volume: 7 Issue: 4
Author(s): M. P. Domingo, J. Pardo, V. Cebolla and Eva M. Galvez
Affiliation:
Keywords: Berberine, fluorescent, alkaloid, analysis, medicine, biochemistry
Abstract: Berberine, a fluorescent, aromatic, heterocyclic alkaloid, produced in a diversity of plants, was found to have curative properties in Chinese herbal medicine. Berberine is used as a treatment for gastric and inflammatory diseases and as an antimicrobial agent. More recently the potential of this alkaloid in diverse new medical application like cardiology, neurology and oncology is being investigated. As a result of its fluorescent properties, it has also been used in chemistry to study protein conformation and protein/protein interactions and to quantitate non-fluorescent compounds. All these applications will be summarized and discussed in this review.
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Cite this article as:
P. Domingo M., Pardo J., Cebolla V. and M. Galvez Eva, Berberine: A Fluorescent Alkaloid with a Variety of Applications from Medicine to Chemistry, Mini-Reviews in Organic Chemistry 2010; 7 (4) . https://dx.doi.org/10.2174/157019310792246445
DOI https://dx.doi.org/10.2174/157019310792246445 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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