Abstract
The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a number of biologically active molecules. The purpose of this review is to provide an overview of the pharmacological activity of synthetic caffeic acid analogs including recent reports of anti-inflammatory, anti-cancer, and antiviral activities of these compounds.
Keywords: Caffeic acid, anticancer, antioxidant, anti-inflammatory, integrase inhibitors, structure-activity relationships, Pharmacophore, scaffold, natural products, antiviral, synthetic caffeic acid
Mini-Reviews in Medicinal Chemistry
Title: Caffeic Acid, A Versatile Pharmacophore: An Overview
Volume: 11 Issue: 8
Author(s): M. Touaibia, J. Jean-Francois and J. Doiron
Affiliation:
Keywords: Caffeic acid, anticancer, antioxidant, anti-inflammatory, integrase inhibitors, structure-activity relationships, Pharmacophore, scaffold, natural products, antiviral, synthetic caffeic acid
Abstract: The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a number of biologically active molecules. The purpose of this review is to provide an overview of the pharmacological activity of synthetic caffeic acid analogs including recent reports of anti-inflammatory, anti-cancer, and antiviral activities of these compounds.
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Cite this article as:
Touaibia M., Jean-Francois J. and Doiron J., Caffeic Acid, A Versatile Pharmacophore: An Overview, Mini-Reviews in Medicinal Chemistry 2011; 11 (8) . https://dx.doi.org/10.2174/138955711796268750
DOI https://dx.doi.org/10.2174/138955711796268750 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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