Abstract
An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (Ki < 100 nM).
Keywords: solid-phase synthesis, ccri receptor antagonist
Combinatorial Chemistry & High Throughput Screening
Title: Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists
Volume: 5 Issue: 3
Author(s): Brad O. Buckman, Ameen Ghannam, Angela Li, Meina Liang, Raju Mohan and Howard P. Ng
Affiliation:
Keywords: solid-phase synthesis, ccri receptor antagonist
Abstract: An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (Ki < 100 nM).
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Cite this article as:
Buckman O. Brad, Ghannam Ameen, Li Angela, Liang Meina, Mohan Raju and Ng P. Howard, Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists, Combinatorial Chemistry & High Throughput Screening 2002; 5 (3) . https://dx.doi.org/10.2174/1386207024607284
DOI https://dx.doi.org/10.2174/1386207024607284 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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