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Current Protein & Peptide Science

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ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

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Mini-Review Article

Diabetic Wound: Pathophysiology, Complications and Treatment Strategies

Author(s): Sunita Chauhan, Monika Gulia, Rahul Pratap Singh and Vikas Jhawat*

Volume 25, Issue 3, 2024

Published on: 31 October, 2023

Page: [200 - 205] Pages: 6

DOI: 10.2174/0113892037276171231016103320

Price: $65

Abstract

Diabetic wound healing is expected to affect 25% of all diabetics, resulting in less severe external factors, economic costs, and less trauma. Topical formulations have been continually improved to achieve a range of amazing properties and have had a significant impact on the management of diabetic wounds. Topical insulin has become one of the most attractive and convenient wound healing techniques due to its excellent biocompatibility, water retention, and therapeutic properties. Multiple versatile topical insulins have been identified and have shown promise over the past few years as they greatly facilitate the management of diabetic wounds as we understand their etiology. The physiological wound healing process repairs damaged tissue and restores skin integrity. For about a century, insulin, a powerful healing agent, and it has been utilized in several clinical and experimental researches research studies to accelerate the healing of various injuries.

Keywords: Diabetic complications, diabetic wound, Insulin, topical delivery, PLO gel, wound-healing.

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Graphical Abstract

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