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Gonadal Dysgenesis With a Familial Character

Published online by Cambridge University Press:  01 August 2014

A. M. D. Serban ,
B. Ionescu ,
M. Ciovîrnache ,
A. Damian  and
C. Maximilian
A. M. D. Serban
Affiliation:
Institutul de Endocrinologie “C. I. Parhon”, Bucuresti
B. Ionescu
Affiliation:
Institutul de Endocrinologie “C. I. Parhon”, Bucuresti
M. Ciovîrnache
Affiliation:
Institutul de Endocrinologie “C. I. Parhon”, Bucuresti
A. Damian
Affiliation:
Institutul de Endocrinologie “C. I. Parhon”, Bucuresti
C. Maximilian
Affiliation:
Institutul de Endocrinologie “C. I. Parhon”, Bucuresti

Summary

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The Authors report on a case of congenital anorchidism, confirmed by laparatomy, with negative sexual chromatin and an XY karyotype. One of his two sisters, with primary amenorrhea, presented marked hypoplasia of the genital tract, positive sexual chromatin and in 3% of the cells with 2 chromatine corpuscles, XO/XX/XXX karyotype. The presence in the same family of two cases of gonadal dysgenesis appears to have occurred by mere chance.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 15 , Issue 4 , September 1966 , pp. 386 - 396
Copyright
Copyright © The International Society for Twin Studies 1966

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