The demarcation of permanent prime cultivated land is a method of economical and intensive use of land, and it is one of the effective ways to solve the shortage of cultivated land reserve resources. Taking Qinghe County, Hebei Province as the study area, firstly the cultivated land natural endowments, location conditions, construction levels were considered according to the system of permanent prime cultivated land of China, then the index system of demarcation of permanent prime cultivated land was constructed with result of agricultural land classification, and the cultivated land was classified and partitioned by TOPSIS. The result showed that mainly cultivated land in permanent protection area, adjustment and construction area and primary remediation area was high quality, flat, centralized and contiguous, some of cultivated land could be demarcated as the permanent prime cultivated land. Cultivated land in reserved construction area was low quality, high terrain relief degree, farming difficult and low benefit, and it was not suitable to be demarcated as the permanent prime cultivated land. This study quantified the demarcation of permanent prime cultivated land, and the cultivated land comprehensive quality was sorted by drawing into the TOPSIS, the result could broaden the way of demarcation of permanent prime cultivated land.