With the development of computational fluid dynamics, the simulation accuracy and reliability are improved constantly. This technology is widely used in agricultural cold-chain logistics for the past few years which has significances to raise temperature homogeneity of the low-temperature environment, determine the goods stack, reasonably control refrigerating time, and improve the economic benefits of overall cold-chain logistics. This paper mainly described the pre-processing, computation and post-processing of computational fluid dynamics, reviewed the research advance of it in store, transportation and market process of agricultural cold-chain logistics, expounded the research methods and application characteristics of the technology, generalized and analyzed the advantages and deficiencies. Moreover, the paper also looked into the future trends of computational fluid dynamics in agricultural cold-chain logistics applications.