| About the author: |
O. L. Appelhans, O. V. Kozishkurt, K. S. Gritsenko, N. V. Boruta, T. P. Shabliy, O. А. Hruzevskyi, O. V. Naіdich |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The etiological role of adenoviruses as causative agents of acute diarrhea in the southern region of Ukraine was studied. Adenovirus DNA was detected in 10.61±1.05 % of clinical stool samples. Serotypes of two gene groups: C and F were identified during genotyping and sequencing of genetic material of detected adenovirus isolates. Gene group F (HAdV41), proves their role in the occurrence of this infectious pathology. HAdV41 isolates had a significant advantage 75.0±15.31 % and had a pronounced genetic heterogeneity, showed similarities with serotypes circulating in previous years in different regions of the world: Sweden (1978), Japan (2003, 2006), South Africa (2009–2014), Iraq (2016). The obtained results allowed to establish the geographical origin of circulating adenoviruses, as well as to predict a further increase in the intensity of the epidemic process of adenoviral infections in southern Ukraine. |
| Tags |
acute diarrhea, etiological structure, adenoviral infection, molecular genetic features, epidemic process |
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| Publication of the article |
«World of Medicine and Biology» №2(80), 2022 year, 189-193 pages, index UDK 616.34-008.314.4-002.1-02:616.98:578.826]-056.7-07)477.7) |
| DOI |
10.26724/2079-8334-2022-2-80-189-193 |
