• editor.aipublications@gmail.com
  • Track Your Paper
  • Contact Us
  • ISSN: 2456-8015

International Journal Of Medical, Pharmacy And Drug Research(IJMPD)

An Analysis on the UV-Visible Spectrophotometry Method

Satyendra Singh , Vivek Denial , Manmeet Singh


International Journal of Medical, Pharmacy and Drug Research(IJMPD), Vol-7,Issue-4, July - September 2023, Pages 73-80 , 10.22161/ijmpd.7.4.6

Download | Downloads : 3 | Total View : 381

Article Info: Received: 03 Jul 2023; Received in revised form: 05 Aug 2023; Accepted: 13 Aug 2023; Available online: 18 Aug 2023

Share

In the pharmaceutical industry, quality control is a necessary process. Pharmaceutical medicinal products must be advertised as safe, therapeutically active formulations with predictable qualities and performance. The main aim of the study is an analysis on the UV-Visible Spectrophotometry Method. UV spectroscopy was performed on Shimadzu 1700 uv spectrometer, 1cm cell quartz cuvette. Mode was set as UV mode and Detector wavelength was kept at 231 nm and 276 nm. A simple, rapid, accurate, sensitive and cost economical methodology for simultaneous estimation and precise ultraviolet radiation methodology has been developed and valid as per ICH guidelines for simultaneous Estimation of MET and AGP in Their Combined dose form.

pharmaceutical, therapeutically, Spectrophotometry, economical, Estimation

[1] Aravind A, Das P, TK AB, George M. Q-Absorbance Ratio Spectrophotometric Method For The Simultaneous Estimation Of Metformin Hydrochloride And Pioglitazone In Tablet Dosage Form.
[2] Habash IW, Al-Shdefat RI, Hailat MM, Dayyih WA. A Stability Indicating RP-HPLC Method Development for Simultaneous Estimation of Alogliptin, Pioglitazone, and
[3] Godge RK, Shinde GS, Bhosale MS. RP-HPLC Method for estimation of Alogliptin and Glibenclamide in Synthetic mixture. Research Journal of Pharmacy and Technology. 2020 Feb 1;13(2):555-9.
[4] Mahrouse MA, Lamie NT. Experimental design methodology for optimization and robustness determination in ion pair RP-HPLC method development: Application for the simultaneous determination of metformin hydrochloride, alogliptin benzoate and repaglinide in tablets. Microchemical Journal. 2019 Jun 1; 147:691-706.
[5] KB P, Sandhyavali MS, Murugan V, Banu S. Chemometrics Assisted Simultaneous Spectrophotometric Determination of Alogliptin and Metformin in Pharmaceutical Dosage Form.
[6] Naseef H, Moqadi R, Qurt M. Development and validation of an HPLC method for determination of antidiabetic drug alogliptin benzoate in bulk and tablets. Journal of Analytical Methods in Chemistry. 2018 Sep 24;2018.
[7] Sultana N, Rizwana I. Development and validation of stabilty indicating RP-HPLC method for simultaneous estimation of metformin and Alogliptin in bulk and tablet dosage form. Pharma Innovation. 2018; 7:319-24.
[8] Rendell M, Drincic A, Andukuri R. Alogliptin benzoate for the treatment of type 2 diabetes. Expert Opinion on Pharmacotherapy. 2012 Mar 1;13(4):553-63.
[9] Saisho Y. Alogliptin benzoate for management of type 2 diabetes. Vascular health and risk management. 2015; 11:229.
[10] Klepser TB, Kelly MW. Metformin hydrochloride: an antihyperglycemic agent. American journal of health-system pharmacy. 1997 Apr 15;54(8):893-903.