Clinicomycological Profile and Risk Factors for Dermatophytosis at a Teaching Tertiary Care Centre in North India: A Cross-sectional Study

Title:Clinicomycological Profile and Risk Factors for Dermatophytosis at a Teaching Tertiary Care Centre in North India: A Cross-sectional Study

Volume: 23 Issue: 6

Author(s): Pooja Singla*, Sima Garg, Prashant Singh, Nidhi Sharma, Pratibha Mane, Nand Kishore Singh and Sudhanshu Sharma

Affiliation:

• Department of Microbiology, SHKM GMC, Nalhar, India

Keywords: Dermatophytes, trichophyton, KOH microscopy, steroids, antifungals, keratinophilic.

Abstract:

Background: Dermatophytosis has gained significant importance in recent years owing to increased incidence, more atypical lesions, changing mycological profile and growing antifungal resistance. Therefore, this study was planned to know the clinicomycological profile of dermatophytic infections in patients attending our tertiary care centre.

Materials and Methods: A total of 700 patients with superficial fungal infections belonging to all age groups and both sexes were taken up for this cross-sectional study. Sociodemographic and clinical details were noted on a prestructured proforma. Superficial lesions were clinically examined and the sample was collected by appropriate collection methods. Direct microscopy by potassium hydroxide wet mount was done to see hyphae. For culture Sabouraud’s dextrose agar (SDA) with chloramphenicol and cyclohexamide was used.

Results: Dermatophytic infections were detected in 75.8% (531/700) patients. Young people belonging to age group of 21-30 years were commonly affected. Tinea corporis was the commonest clinical picture seen in 20% of the cases. Oral antifungals were taken by 33.1% and topical creams were used by 74.2% of the patients. Direct microscopy was positive in 91.3% and culture was positive for dermatophytes in 61% of the study subjects. T. mentagrophytes was the commonest dermatophyte isolated.

Conclusion: Irrational use of topical steroids needs to be controlled. KOH microscopy can be useful as a point of care test for rapid screening of dermatophytic infections. Culture is necessary to differentiate various dermatophytes and to guide the antifungal treatment.

Cite this article as:

Singla Pooja*, Garg Sima, Singh Prashant, Sharma Nidhi, Mane Pratibha, Singh Kishore Nand and Sharma Sudhanshu, Clinicomycological Profile and Risk Factors for Dermatophytosis at a Teaching Tertiary Care Centre in North India: A Cross-sectional Study, Infectious Disorders - Drug Targets 2023; 23 (6) : e280423216334 . https://dx.doi.org/10.2174/1871526523666230428110207