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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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Review Article

A Synopsis of Ball Milling Organic Synthesis in the Last 25 Years

Author(s): Davor Margetić*

Volume 27, Issue 7, 2023

Published on: 27 April, 2023

Page: [580 - 584] Pages: 5

DOI: 10.2174/1385272827666230407082210

open access plus

Abstract

Important progress in the transfer of organic reactions from solution conditions to automated solid-state synthesis was published a quarter of a century ago. Since then, ball-milling organic reactions have been slowly accepted by the chemical community as an additional synthetic tool, and the area of its application is rapidly expanding. These developments in mechanochemical synthesis are illustrated with selected literature examples.

Keywords: Organic synthesis, solid-state reactions, mechanochemistry, mechanochemical synthesis, manual grinding, fullerene derivatives.

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