Incidence Rate of Post Coronary Artery Shunt Complications; Age Dependent!

Title:Incidence Rate of Post Coronary Artery Shunt Complications; Age Dependent!

Volume: 22

Author(s): Basheer Abdullah Marzoog*

Affiliation:

• World-Class Research Center, Digital Biodesign and Personalized Healthcare, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia; Postal Address: Russia, Moscow, 8-2 Trubetskaya street, 119991

Keywords: Surgery, Myocardial Infarction, Angioplasty, CABG, CVD & CVS, progressive Angina

Abstract: Background: Numerous complications, such as postoperative arrhythmia and stroke, have been observed following coronary artery bypass graft (CABG) surgery. Aims: This study sought to examine the impact of aging on the incidence of post-coronary artery shunt complications.

Objectives: Aging is a physiological process experienced by every living cell, beginning early in development. Age plays a crucial role in determining postoperative complications, including those related to CABG.

Materials and Methods: A retrospective analysis was conducted on 290 patients who underwent CABG at the Mordovian Republic Hospital between 2017 and 2021. The sample was divided into two age-based groups: the first group comprised 126 patients (mean age range: 55.21-60.00), and the second group included 163 patients (mean age range: 66.11-80.00). Statistical analyses employed in this study encompassed descriptive statistics, Chi-square test, T-test, one-way ANOVA test, ROC analysis, and Pearson correlation using Statistica 12 software.

Results: Elderly patients in the second group demonstrated a higher incidence of post-CABG arrhythmia (p<0.012528). Moreover, the second group experienced markedly longer ICU and total hospitalization days following CABG, with p-values of less than 0.000000 and 0.000072, respectively. Notably, elderly individuals in the second group faced an increased risk of developing psychosis after CABG surgery (p<0.007379). Furthermore, psychosis was found to be significantly associated with longer ICU hospitalization (p<0.000140). Postoperative stroke occurred more frequently among the elderly (second group) with a p-value of less than 0.037736. Consequently, postoperative stroke was associated with extended ICU hospitalization (p<0.000747). The usage of internal thoracic arteries (ITAs) was lower among the elderly (second group), with a p-value of less than 0.016145. Regarding correlations, a direct association was observed between age and ICU days, total hospitalization days, and the number of complications, with correlation coefficients (r) of 0.189046, 0.141415, and 0.138565, respectively.

Conclusion: Elderly individuals in the second group who undergo CABG face a greater risk of developing psychosis, arrhythmia, prolonged total and ICU hospitalization, and stroke. The presence of arrhythmia, which is commonly observed in patients aged 63 years and older, significantly affects total hospitalization days. The number of complications is influenced by age, cardiopulmonary bypass (CPB) time, aortic cross-clamp time, ICU hospitalization, and total hospitalization duration.

Cite this article as:

Marzoog Basheer Abdullah*, Incidence Rate of Post Coronary Artery Shunt Complications; Age Dependent!, Cardiovascular & Hematological Agents in Medicinal Chemistry 2024; 22 () . https://dx.doi.org/10.2174/0118715257265595231128070227