Skip to main content
Log in

Three cases of laparoscopic myomectomy performed during pregnancy for pedunculated uterine myomas

  • General Gynecology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

Laparoscopic myomectomy during pregnancy is indicated when symptoms related to uterine myomas persist despite pharmacologic therapy; however, currently there is very little information concerning its safety.

Methods

We report three cases of antepartum laparoscopic myomectomy performed to manage complicated myomas requiring surgical intervention.

Results

In particular, we report for the first time in literature the laparoscopic removal of two myomas in a patient during a single surgery performed in the 19th week of pregnancy followed by additional multiple myomectomy at the time of the cesarean section. All surgeries were without complication.

Conclusions

Our experience suggests that laparoscopic myomectomy may be performed safely during pregnancy; even more studies are needed to establish the exact rate of adverse events.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Qidwai GI, Caughey AB, Jacoby AF (2006) Obstetric outcomes in women with sonographically identified uterine leiomyomata. Obstet Gynecol 107(2 Pt 1):376–382

    Article  PubMed  Google Scholar 

  2. Laughlin SK, Baird DD, Savitz DA, Herring AH, Hartmann KE (2009) Prevalence of uterine leiomyomas in the first trimester of pregnancy: an ultrasound-screening study. Obstet Gynecol 113:630–635

    PubMed  Google Scholar 

  3. Rice JP, Kay HH, Mahony BS (1989) The clinical significance of uterine leiomyomas in pregnancy. Am J Obstet Gynecol 160:1212–1216

    PubMed  CAS  Google Scholar 

  4. Zaima A, Ash A (2011) Fibroid in pregnancy: characteristics, complications, and management. Postgrad Med J 87:819–828

    Article  PubMed  Google Scholar 

  5. Ouyang DW, Economy KE, Norwitz ER (2006) Obstetric complications of fibroids. Obstet Gynecol Clin N Am 33:153–169

    Article  Google Scholar 

  6. Benson CB, Chow JS, Chang-Lee W, Hill JA 3rd, Doubilet PM (2001) Outcome of pregnancies in women with uterine leiomyomas identified by sonography in the first trimester. J Clin Ultrasound 29:261–264

    Article  PubMed  CAS  Google Scholar 

  7. Noor S, Fawwad A, Sultana R, Bashir R, Qurat-ul-ain Jalil H, Suleman N, Khan A (2009) Pregnancy with fibroids and its obstetric complication. J Ayub Med Coll Abbottabad 21:37–40

    PubMed  Google Scholar 

  8. Vergani P, Ghidini A, Strobelt N, Roncaglia N, Locatelli A, Lapinski RH, Mangioni C (1994) Do uterine leiomyomas influence pregnancy outcome? Am J Perinatol 11:356–358

    Article  PubMed  CAS  Google Scholar 

  9. Exacoustòs C, Rosati P (1993) Ultrasound diagnosis of uterine myomas and complications in pregnancy. Obstet Gynecol 82:97–101

    PubMed  Google Scholar 

  10. Lolis DE, Kalantaridou SN, Makrydimas G, Sotiriadis A, Navrozoglou I, Zikopoulos K, Paraskevaidis EA (2003) Successful myomectomy during pregnancy. Hum Reprod 18:1699–1702

    Article  PubMed  CAS  Google Scholar 

  11. Mu YL, Wang S, Hao J, Shi M, Yelian FD, Wang XT (2011) Successful pregnancies with uterine leiomyomas and myomectomy at the time of caesarean section. Postgrad Med J 87:601–604

    Article  PubMed  Google Scholar 

  12. Ande AB, Ehigiegba AE, Umeora OU (2004) Repeat myomectomy at caesarean section. Arch Gynecol Obstet 270:296–298

    Article  PubMed  Google Scholar 

  13. Lozza V, Pieralli A, Corioni S, Longinotti M, Penna C (2011) Multiple laparotomic myomectomy during pregnancy: a case report. Arch Gynecol Obstet 284:613–616

    Article  PubMed  CAS  Google Scholar 

  14. Gupta S, Manyonda IT (2009) Acute complications of fibroids. Best Pract Res Clin Obstet Gynaecol 23:609–617

    Article  PubMed  Google Scholar 

  15. Ardovino M, Ardovino I, Castaldi MA, Monteverde A, Colacurci N, Cobellis L (2011) Laparoscopic myomectomy of a subserous pedunculated fibroid at 14 weeks of pregnancy: a case report. J Med Case Rep 5:545

    Article  PubMed  Google Scholar 

  16. Bhatla N, Dash BB, Kriplani A, Agarwal N (2009) Myomectomy during pregnancy: a feasible option. J Obstet Gynaecol Res 35:173–175

    Article  PubMed  Google Scholar 

  17. Fatum M, Rojansky N (2001) Laparoscopic surgery during pregnancy. Obstet Gynecol Surv 56:50–59

    Article  PubMed  CAS  Google Scholar 

  18. Stepp KJ, Tulikangas PK, Goldberg JM, Attaran M, Falcone T (2003) Laparoscopy for adnexal masses in the second trimester of pregnancy. J Am Assoc Gynecol Laparosc 10:55–59

    Article  PubMed  Google Scholar 

  19. Corneille MG, Gallup TM, Bening T, Wolf SE, Brougher C, Myers JG, Dent DL, Medrano G, Xenakis E, Stewart RM (2010) The use of laparoscopic surgery in pregnancy: evaluation of safety and efficacy. Am J Surg 200:363–367

    Article  PubMed  Google Scholar 

  20. Chohan L, Kilpatrick CC (2009) Laparoscopy in pregnancy: a literature review. Clin Obstet Gynecol 52:557–569

    Article  PubMed  Google Scholar 

  21. Djakovic A, Hönig A, Gross M, Dietl J (2006) Adnexal torsion in a patient with bichorial twin pregnancy in the 21st week of gestation treated by open laparoscopy: a case report. Arch Gynecol Obstet 274:248–249

    Article  PubMed  Google Scholar 

  22. Kuczkowski KM (2007) Laparoscopic procedures during pregnancy and the risks of anesthesia: what does an obstetrician need to know? Arch Gynecol Obstet 276:201–209

    Article  PubMed  Google Scholar 

  23. Cheek TG, Baird E (2009) Anesthesia for nonobstetric surgery: maternal and fetal considerations. Clin Obstet Gynecol 52:535–545

    Article  PubMed  Google Scholar 

  24. Son CE, Choi JS, Lee JH, Jeon SW, Bae JW, Seo SS (2011) A case of laparoscopic myomectomy performed during pregnancy for subserosal uterine myoma. J Obstet Gynaecol 31:180–181

    Article  PubMed  CAS  Google Scholar 

  25. Pelosi MA, Pelosi MA 3rd, Giblin S (1995) Laparoscopic removal of a 1500-g symptomatic myoma during the second trimester of pregnancy. J Am Assoc Gynecol Laparosc 2:457–462

    Article  PubMed  CAS  Google Scholar 

  26. Fanfani F, Rossitto C, Fagotti A, Rosati P, Gallotta V, Scambia G (2010) Laparoscopic myomectomy at 25 weeks of pregnancy: case report. J Minim Invasive Gynecol 17:91–93

    Article  PubMed  Google Scholar 

  27. Friedman JD, Ramsey PS, Ramin KD, Berry C (2002) Pneumoamnion and pregnancy loss after second trimester laparoscopic surgery. Obstet Gynecol 99:512–513

    Article  PubMed  Google Scholar 

  28. Sentilhes L, Sergent F, Verspyck E, Gravier A, Roman H, Marpeau L (2003) Laparoscopic myomectomy during pregnancy resulting in septic necrosis of the myometrium. BJOG 110:876–878

    Article  PubMed  CAS  Google Scholar 

  29. Al-Fozan H, Tulandi T (2002) Safety and risks of laparoscopy in pregnancy. Curr Opin Obstet Gynecol 14:375–379

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

Work supported by “Associazione sarda per la ricerca in oncologia ginecologica- ONLUS”. The authors thank Marisa Pilia, Alessandra Arca, Agostina Aversano, Luca Calia, Renzo Mongittu, Anna Rita Oi, Cinzia Palazzari and Stefano Piga for their technical assistance.

Conflict of interest

No conflict of interest has to be declared.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Antonio Macciò.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Macciò, A., Madeddu, C., Kotsonis, P. et al. Three cases of laparoscopic myomectomy performed during pregnancy for pedunculated uterine myomas. Arch Gynecol Obstet 286, 1209–1214 (2012). https://doi.org/10.1007/s00404-012-2441-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-012-2441-0

Keywords

Navigation