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Supplemental Information

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Yan Li conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Zhijun Li conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Qing Sun performed the experiments, wrote the paper.

Mengying Wang analyzed the data.

Meng Jiang analyzed the data.

Yutong Zhou analyzed the data.

Guanyu Wu analyzed the data.

Yali Qi conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Written informed consent form was obtained from children and adolescents and their parents. Ethical approval was obtained from Beihua University School of Public Health, and written informed consent was obtained from all subjects.

Data Deposition

The following information was supplied regarding data availability:

The raw data or code is owned by a third-party who has not given their permission to publish as part of this manuscript. For ethical reasons to maintain confidentiality.

Funding

Jilin Province Education Department "Twelve Five" Science and Technology Research Project (2014-192). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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