Compile Data Set for Download or QSAR
maximum 50k data
Found 120 Enz. Inhib. hit(s) with all data for entry = 50038633
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262603(2,4-Diamino-5-propyl-6-(1'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50377948(CHEMBL476548)
Affinity DataIC50:  60nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262763(2,4-Diamino-5-isopropyl-6-(phenylsulfanyl)-7H-pyrr...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041943(6-(2,5-Dimethoxy-benzyl)-5-methyl-thieno[2,3-d]pyr...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262599(2,4-Diamino-5-propyl-6-(phenylsulfanyl)-7H-pyrrolo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262805(2,4-Diamino-5-isopropyl-6-(1'-naphthylsulfanyl)-7H...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50377949(CHEMBL476751)
Affinity DataIC50:  186nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262600(2,4-Diamino-5-propyl-6-(4'-methoxyphenylsulfanyl)-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262762(2,4-Diamino-5-isopropyl-6-(2',6'-dimethylphenylsul...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262761(2,4-Diamino-5-isopropyl-6-(2',6'-dichlorophenylsul...)
Affinity DataIC50:  520nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262764(2,4-Diamino-5-isopropyl-6-(4'-methoxyphenylsulfany...)
Affinity DataIC50:  600nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262805(2,4-Diamino-5-isopropyl-6-(1'-naphthylsulfanyl)-7H...)
Affinity DataIC50:  910nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262602(2,4-Diamino-5-propyl-6-(3',4'-dimethoxyphenylsulfa...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262599(2,4-Diamino-5-propyl-6-(phenylsulfanyl)-7H-pyrrolo...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262600(2,4-Diamino-5-propyl-6-(4'-methoxyphenylsulfanyl)-...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262765(2,4-Diamino-5-isopropyl-6-(2',5'-dimethoxyphenylsu...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262599(2,4-Diamino-5-propyl-6-(phenylsulfanyl)-7H-pyrrolo...)
Affinity DataIC50: >1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262601(2,4-Diamino-5-propyl-6-(2',5'-dimethoxyphenylsulfa...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262807(2,4-Diamino-5-isopropyl-6-(3',4'-dichlorophenylsul...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262806(-Diamino-5-isopropyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262764(2,4-Diamino-5-isopropyl-6-(4'-methoxyphenylsulfany...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262763(2,4-Diamino-5-isopropyl-6-(phenylsulfanyl)-7H-pyrr...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262806(-Diamino-5-isopropyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262761(2,4-Diamino-5-isopropyl-6-(2',6'-dichlorophenylsul...)
Affinity DataIC50: >2.20E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262761(2,4-Diamino-5-isopropyl-6-(2',6'-dichlorophenylsul...)
Affinity DataIC50: >2.20E+3nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262807(2,4-Diamino-5-isopropyl-6-(3',4'-dichlorophenylsul...)
Affinity DataIC50: >2.30E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262766(2,4-Diamino-5-isopropyl-6-(3',4'-dimethoxyphenylsu...)
Affinity DataIC50: >2.30E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262765(2,4-Diamino-5-isopropyl-6-(2',5'-dimethoxyphenylsu...)
Affinity DataIC50: >2.30E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262807(2,4-Diamino-5-isopropyl-6-(3',4'-dichlorophenylsul...)
Affinity DataIC50: >2.30E+3nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262766(2,4-Diamino-5-isopropyl-6-(3',4'-dimethoxyphenylsu...)
Affinity DataIC50: >2.30E+3nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262765(2,4-Diamino-5-isopropyl-6-(2',5'-dimethoxyphenylsu...)
Affinity DataIC50: >2.30E+3nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262806(-Diamino-5-isopropyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50: >2.40E+3nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262761(2,4-Diamino-5-isopropyl-6-(2',6'-dichlorophenylsul...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262806(-Diamino-5-isopropyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50: >2.40E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262598(2,4-Diamino-5-propyl-6-(2',6'-dimethylphenylsulfan...)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262764(2,4-Diamino-5-isopropyl-6-(4'-methoxyphenylsulfany...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262764(2,4-Diamino-5-isopropyl-6-(4'-methoxyphenylsulfany...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50263299(2,4-Diamino-5-propyl-6-(2',6'-dichlorophenylsulfan...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262763(2,4-Diamino-5-isopropyl-6-(phenylsulfanyl)-7H-pyrr...)
Affinity DataIC50: >2.70E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262763(2,4-Diamino-5-isopropyl-6-(phenylsulfanyl)-7H-pyrr...)
Affinity DataIC50: >2.70E+3nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262766(2,4-Diamino-5-isopropyl-6-(3',4'-dimethoxyphenylsu...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 120 total ) | Next | Last >>
Jump to: