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Found 22 Enz. Inhib. hit(s) with all data for entry = 50033214
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341506(CHEMBL1765627 | N-(5-(3-(2H-Tetrazol-5-yl)imidazo[...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341493(CHEMBL1765463 | Ethyl 6-(5-(Phenylsulfonamido)pyri...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341496(CHEMBL1765617 | N-(5-(3-(2H-Tetrazol-5-yl)imidazo[...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341505(2,4-Difluoro-N-(5-(3-(5-methyl-1,2,4-oxadiazol-3-y...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341491(CHEMBL1765461 | N-(5-(3-Acetylimidazo[1,2-a]pyridi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341501(CHEMBL1765622 | N-(5-(3-(Pyridin-4-yl)imidazo[1,2-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341500(CHEMBL1765621 | N-(5-(3-(Pyridin-3-yl)imidazo[1,2-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341504(CHEMBL1765625 | N-(5-(3-Cyanoimidazo[1,2-a]pyridin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341492(CHEMBL1765462 | N-(5-(3-Cyanoimidazo[1,2-a]pyridin...)
Affinity DataIC50:  11nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341499(CHEMBL1765620 | N-(5-(3-(3-Cyanophenyl)imidazo[1,2...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341497(CHEMBL1765618 | N-(5-(3-Morpholinoimidazo[1,2-a]py...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341502(6-(6-Amino-5-(morpholinosulfonyl)pyridin-3-yl)imid...)
Affinity DataIC50:  47nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341507(3,5-Difluoro-N-(5-(3-(5-methyl-1,2,4-oxadiazol-3-y...)
Affinity DataIC50:  81nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341495(CHEMBL1765465 | N-(5-(3-(1H-Pyrazol-3-yl)imidazo[1...)
Affinity DataIC50:  213nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341490(CHEMBL1765460 | N-(5-(Imidazo[1,2-a]pyridin-6-yl)p...)
Affinity DataIC50:  360nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341503(5-(3-morpholinoimidazo[1,2-a]pyridin-6-yl)-3-(morp...)
Affinity DataIC50:  480nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341498(CHEMBL1765619 | N-(5-(3-Phenylimidazo[1,2-a]pyridi...)
Affinity DataIC50:  720nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 19(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  88nMAssay Description:Binding affinity to CDK11 by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  39nMAssay Description:Binding affinity to mTOR by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to PIK3CA by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  25nMAssay Description:Binding affinity to PIK3CB by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed