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Found 43 Enz. Inhib. hit(s) with all data for entry = 50016868
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]-acetylated histones from human HDAC1 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [3H]-acetylated histones from human HDAC2 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50597917(CHEMBL5193563)
Affinity DataIC50:  41nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50:  80nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  96nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  180nMAssay Description:Displacement of [3H]-acetylated histones from HDAC1 derived from human K562 cell nuclear extract incubated for 10 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  540nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  550nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50:  610nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  740nMAssay Description:Displacement of [3H]-acetylated histones from HDAC3 derived from human K562 cell nuclear extract incubated for 10 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  790nMAssay Description:Displacement of [3H]-acetylated histones from mouse HDAC6 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  850nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataIC50:  6.27E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50597917(CHEMBL5193563)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-acetylated histones HDAC6 derived from human K562 cell nuclear extract incubated for 10 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM36184(4-phenylbutanoate)
Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM26109(Butyrate | butanoic acid | butanoic acid, 4)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM26109(Butyrate | butanoic acid | butanoic acid, 4)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM26109(Butyrate | butanoic acid | butanoic acid, 4)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed