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Found 11 Enz. Inhib. hit(s) with all data for entry = 50049190
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50385568(CHEMBL2040640)
Affinity DataIC50:  190nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) PA endonuclease using ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50385503(CHEMBL2040554)
Affinity DataIC50:  320nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50122448(CHEMBL463590 | L-742001)
Affinity DataIC50:  430nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) PA endonuclease using ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50385528(CHEMBL2040586)
Affinity DataIC50:  540nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) PA endonuclease using ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50385531(CHEMBL2040602)
Affinity DataIC50:  800nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50125833(3-(4-Fluoro-benzylidene)-1-hydroxy-5-isobutyl-3H-p...)
Affinity DataIC50:  900nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) N-terminal PA endonuclease using 880 nucleotide ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50385529(CHEMBL2040587)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) PA endonuclease using ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50385534(CHEMBL2040605)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) N-terminal PA endonuclease using 880 nucleotide ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50385535(CHEMBL2040606)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) N-terminal PA endonuclease using 880 nucleotide ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50125822(1-Hydroxy-5-isobutyl-3-isobutylidene-3H-pyrazine-2...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) N-terminal PA endonuclease using 880 nucleotide ALMV cap1 primer RNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM33410(CHEMBL16755 | N-hydroxyisoquinolinedione, 2)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of influenza A virus (A/PR/8/34) PA endonuclease using ALMV cap1 primer RNA as substrate after 90 mins by scintillation countingMore data for this Ligand-Target Pair