Compile Data Set for Download or QSAR
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Found 49 Enz. Inhib. hit(s) with all data for entry = 50047274
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156774(CHEMBL3792888)
Affinity DataKi:  0.200nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156788(CHEMBL3794104)
Affinity DataKi:  0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156799(CHEMBL3793004)
Affinity DataKi:  0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156784(CHEMBL3792673)
Affinity DataKi:  0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156782(CHEMBL3792663)
Affinity DataKi:  0.600nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156732(CHEMBL3793497)
Affinity DataKi:  0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156683(CHEMBL3793788)
Affinity DataKi:  0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156687(CHEMBL3793029)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156787(CHEMBL3793404)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148579(CHEMBL3770836)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156685(CHEMBL3792412)
Affinity DataKi:  0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156789(CHEMBL3793505)
Affinity DataKi:  0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156780(CHEMBL3794298)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156793(CHEMBL3792921)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156691(CHEMBL3792435)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156795(CHEMBL3794270)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156794(CHEMBL3792666)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156733(CHEMBL3793296)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156786(CHEMBL3793489)
Affinity DataKi:  1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156791(CHEMBL3793969)
Affinity DataKi:  1.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156790(CHEMBL3792549)
Affinity DataKi:  1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156777(CHEMBL3793516)
Affinity DataKi:  1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156783(CHEMBL3792734)
Affinity DataKi:  1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50148578(CHEMBL3770730)
Affinity DataKi:  1.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156797(CHEMBL3793538)
Affinity DataKi:  1.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156684(CHEMBL3793688)
Affinity DataKi:  1.60nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156688(CHEMBL3792969)
Affinity DataKi:  1.70nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156734(CHEMBL3793235)
Affinity DataKi:  1.80nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156711(CHEMBL3792599)
Affinity DataKi:  1.80nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156778(CHEMBL3793153)
Affinity DataKi:  2nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156776(CHEMBL3792593)
Affinity DataKi:  2nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156792(CHEMBL3792581)
Affinity DataKi:  2nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156796(CHEMBL3792781)
Affinity DataKi:  2.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156735(CHEMBL3793203)
Affinity DataKi:  2.70nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156775(CHEMBL3792689)
Affinity DataKi:  3nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156690(CHEMBL3794444)
Affinity DataKi:  3.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156785(CHEMBL3794198)
Affinity DataKi:  3.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156686(CHEMBL3794389 | US11485707, Example 23)
Affinity DataKi:  4.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156692(CHEMBL3792612)
Affinity DataKi:  4.80nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156781(CHEMBL3794254)
Affinity DataKi:  5.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156729(CHEMBL3794435)
Affinity DataKi:  6.80nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156779(CHEMBL3793368)
Affinity DataKi:  10nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156798(CHEMBL3793245)
Affinity DataKi:  16nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156689(CHEMBL3793243)
Affinity DataKi:  22nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156731(CHEMBL3793381)
Affinity DataKi:  42nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156694(CHEMBL3793870)
Affinity DataKi:  275nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156730(CHEMBL3793659)
Affinity DataKi:  359nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156707(CHEMBL3792603)
Affinity DataKi:  821nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed