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Found 42 Enz. Inhib. hit(s) with all data for entry = 2933
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385580(US10287279, Compound 22)
Affinity DataIC50:  100nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385581(US10287279, Compound 23)
Affinity DataIC50:  120nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385579(US10287279, Compound 21)
Affinity DataIC50:  120nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50:  200nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50:  200nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50:  200nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385582(US10287279, Compound 24)
Affinity DataIC50:  300nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385565(US10287279, Compound 7)
Affinity DataIC50:  460nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385590(US10287279, Compound 32)
Affinity DataIC50:  550nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385563(US10287279, Compound 5)
Affinity DataIC50:  730nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385566(US10287279, Compound 8)
Affinity DataIC50:  810nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385583(US10287279, Compound 25)
Affinity DataIC50:  3.00E+3nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385562(US10287279, Compound 4)
Affinity DataIC50:  3.60E+3nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385572(US10287279, Compound 14)
Affinity DataIC50:  3.90E+3nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385593(US10287279, Compound 35)
Affinity DataIC50:  5.40E+3nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385574(US10287279, Compound 16)
Affinity DataIC50:  6.30E+3nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385568(US10287279, Compound 10)
Affinity DataIC50:  7.60E+3nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385585(US10287279, Compound 27)
Affinity DataIC50:  1.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385575(US10287279, Compound 17)
Affinity DataIC50:  1.50E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385570(US10287279, Compound 12)
Affinity DataIC50:  2.30E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385577(US10287279, Compound 19)
Affinity DataIC50:  2.50E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385588(US10287279, Compound 30)
Affinity DataIC50: >2.50E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385573(US10287279, Compound 15)
Affinity DataIC50:  2.50E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385559(US10287279, Compound 1 | US10287279, Compound 20)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385561(US10287279, Compound 3)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385560(US10287279, Compound 2)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385596(US10287279, Compound 38)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385587(US10287279, Compound 29)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385586(US10287279, Compound 28)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM50011789(CHEMBL3262931 | US10287279, Compound 39)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385569(US10287279, Compound 11)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385589(US10287279, Compound 31)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385567(US10287279, Compound 9)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385564(US10287279, Compound 6)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385591(US10287279, Compound 33)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385592(US10287279, Compound 34)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM50011790(CHEMBL3262932 | US10287279, Compound 40)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385594(US10287279, Compound 36)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385595(US10287279, Compound 37)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385571(US10287279, Compound 13)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385584(US10287279, Compound 26)
Affinity DataIC50: >4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
The Children'S Hospital

US Patent
LigandPNGBDBM385576(US10287279, Compound 18)
Affinity DataIC50: >5.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent