Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 8761
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397111(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(2-thiaz...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397141(US10456385, Example 46 | US9987259, Example 46)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397113(N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(2-...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397114(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-chloro-2-py...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397115(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-pheny...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397116(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-[3-pheny...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397117(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-methyl-2-th...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397118(N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1-(5-methyl...)
Affinity DataEC50: <100nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397119(N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1-(5-methyl...)
Affinity DataEC50:  750nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397120(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-ethyl-2-thi...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397121(N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1-(5-ethyl-...)
Affinity DataEC50: <100nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397122(N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1-(5-ethyl-...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397123(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-propy...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397124(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-propa...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397125(N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-...)
Affinity DataEC50: <100nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397126(N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397127(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-tert-butyl-...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397128(N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1-[5-tert-b...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397129(N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1-[5-tert-b...)
Affinity DataEC50:  750nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397130(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-cyclopentyl...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397131(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-cyclohexyl-...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397132(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-phenyl-2-th...)
Affinity DataEC50:  750nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397133(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(5-chloro-2-th...)
Affinity DataEC50: <100nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397134(N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1-(5-chloro...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397135(N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1-(5-chloro...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397136(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-[5-(phen...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397137(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(4-methyl-2-th...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397138(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-(1,3-benzothia...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397139(N-(1-azabicyclo[2.2.2]octan-3-yl)-1-[5-methyl-1,3,...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397140((1-azabicyclo[2.2.2]octan-3-yl)-1-[5-methyl-1,3-th...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397112(N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(2-...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent