Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50032435
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329182(CHEMBL1269261 | N-benzyl-N-isopropyl-2-(5-oxo-1-ph...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]CCK8 from rat CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329179(2-((4S)-4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4...)
Affinity DataIC50:  12.2nMAssay Description:Displacement of [125I]CCK8 from rat CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329184(CHEMBL1269262 | N-benzyl-N-isopropyl-2-(5-oxo-4-ph...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329181(3-(6-(2-(benzyl(isopropyl)amino)-2-oxoethyl)-5-oxo...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]CCK8 from rat CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329180(3-((6-(2-(isopropyl(phenyl)amino)-2-oxoethyl)-5-ox...)
Affinity DataIC50:  19.7nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329185(2-(4-(1H-indazol-3-yl)-5-oxo-1-phenyl-4H-benzo[b][...)
Affinity DataIC50:  21nMAssay Description:Displacement of [125I]CCK8 from rat CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329182(CHEMBL1269261 | N-benzyl-N-isopropyl-2-(5-oxo-1-ph...)
Affinity DataIC50:  24.3nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329179(2-((4S)-4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4...)
Affinity DataIC50:  31.7nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329185(2-(4-(1H-indazol-3-yl)-5-oxo-1-phenyl-4H-benzo[b][...)
Affinity DataIC50:  48.5nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329181(3-(6-(2-(benzyl(isopropyl)amino)-2-oxoethyl)-5-oxo...)
Affinity DataIC50:  49.3nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataIC50:  52.6nMAssay Description:Displacement of [125I]CCK8 from rat CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataIC50:  131nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329183(2-(4-benzyl-5-oxo-1-phenyl-4H-benzo[b][1,2,4]triaz...)
Affinity DataIC50:  201nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329186(2-((4R)-4-(1H-indol-3-yl)-5-oxo-1-phenyl-4H-benzo[...)
Affinity DataIC50:  246nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329179(2-((4S)-4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4...)
Affinity DataEC50:  446nMAssay Description:Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329181(3-(6-(2-(benzyl(isopropyl)amino)-2-oxoethyl)-5-oxo...)
Affinity DataEC50:  428nMAssay Description:Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329182(CHEMBL1269261 | N-benzyl-N-isopropyl-2-(5-oxo-1-ph...)
Affinity DataEC50:  294nMAssay Description:Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  63.8nMAssay Description:Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329186(2-((4R)-4-(1H-indol-3-yl)-5-oxo-1-phenyl-4H-benzo[...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329185(2-(4-(1H-indazol-3-yl)-5-oxo-1-phenyl-4H-benzo[b][...)
Affinity DataEC50:  522nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329184(CHEMBL1269262 | N-benzyl-N-isopropyl-2-(5-oxo-4-ph...)
Affinity DataEC50:  628nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329183(2-(4-benzyl-5-oxo-1-phenyl-4H-benzo[b][1,2,4]triaz...)
Affinity DataEC50:  1.81E+3nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329185(2-(4-(1H-indazol-3-yl)-5-oxo-1-phenyl-4H-benzo[b][...)
Affinity DataEC50:  481nMAssay Description:Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329181(3-(6-(2-(benzyl(isopropyl)amino)-2-oxoethyl)-5-oxo...)
Affinity DataEC50:  645nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329180(3-((6-(2-(isopropyl(phenyl)amino)-2-oxoethyl)-5-ox...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329179(2-((4S)-4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4...)
Affinity DataEC50:  315nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  283nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329182(CHEMBL1269261 | N-benzyl-N-isopropyl-2-(5-oxo-1-ph...)
Affinity DataEC50:  91.3nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed