Found 50 Enz. Inhib. hit(s) with all data for entry = 50045317 
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of HCC4-induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of RANTES-induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]hMIP-1alpha from CCR1 in human PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of HCC1-induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MCP3-induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MPIF1-induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of LKN1-induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CCR1 receptor in human whole blood assessed as blocked of MIP-1alpha-mediated CD11b upregulation preincubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Antagonist activity at CCR1 receptor in human whole blood assessed as blocked of LKN1-mediated CD11b upregulation preincubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 635nMAssay Description:Displacement of [125I]hMIP-1alpha from dog PBMC CCR1More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Displacement of [125I]hMIP-1alpha from mouse CCR1More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 7.80E+3nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 1.90E+4nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 5.70E+3nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 2.50E+4nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
