Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50031996
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322919(4-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(triflu...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322918(4-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322917(4-(4-ethoxy-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322919(4-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(triflu...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322925(6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(trifluoro...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322924(6-(4-(3-(2-ethyl-1H-imidazol-1-yl)propoxy)-3-(trif...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313461(4-propyl-6-(3-(trifluoromethyl)phenyl)pyrimidine-2...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322917(4-(4-ethoxy-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313461(4-propyl-6-(3-(trifluoromethyl)phenyl)pyrimidine-2...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322918(4-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322923(6-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(triflu...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322922(6-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  155nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322921(6-(4-ethoxy-3-(trifluoromethyl)phenyl)picolinonitr...)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322923(6-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(triflu...)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322920(6-(3-(trifluoromethyl)phenyl)picolinonitrile | CHE...)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322924(6-(4-(3-(2-ethyl-1H-imidazol-1-yl)propoxy)-3-(trif...)
Affinity DataIC50:  3.09E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322922(6-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322925(6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(trifluoro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322920(6-(3-(trifluoromethyl)phenyl)picolinonitrile | CHE...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322921(6-(4-ethoxy-3-(trifluoromethyl)phenyl)picolinonitr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322923(6-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(triflu...)
Affinity DataEC50:  138nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as induction of accumulation of lip10More data for this Ligand-Target Pair