Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50032876
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336012(6-chloro-8-(4-chlorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336018(6-chloro-8-(3-fluoro-4-methylphenyl)-2-(trifluorom...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336014(6-chloro-8-(4-ethylphenyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336013(6-chloro-8-p-tolyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  103nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331883(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  188nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336016(6-chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethy...)
Affinity DataIC50:  242nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336012(6-chloro-8-(4-chlorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50:  242nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  300nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336019(6-chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoro...)
Affinity DataIC50:  339nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336015(6-chloro-8-(4-ethoxyphenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50:  355nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336011(6-chloro-8-(4-fluorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50:  740nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50:  758nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336006(8-(4-aminophenyl)-6-chloro-2-(trifluoromethyl)-2H-...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331883(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336006(8-(4-aminophenyl)-6-chloro-2-(trifluoromethyl)-2H-...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336008(6-chloro-8-(4-(hydroxymethyl)phenyl)-2-(trifluorom...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336009(6-chloro-8-(4-hydroxyphenyl)-2-(trifluoromethyl)-2...)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336009(6-chloro-8-(4-hydroxyphenyl)-2-(trifluoromethyl)-2...)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336005(6-chloro-8-(4-(methylsulfonyl)phenyl)-2-(trifluoro...)
Affinity DataIC50:  3.87E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336013(6-chloro-8-p-tolyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  4.34E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336008(6-chloro-8-(4-(hydroxymethyl)phenyl)-2-(trifluorom...)
Affinity DataIC50:  6.38E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336017(6-chloro-8-(4-isobutylphenyl)-2-(trifluoromethyl)-...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336014(6-chloro-8-(4-ethylphenyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336005(6-chloro-8-(4-(methylsulfonyl)phenyl)-2-(trifluoro...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336018(6-chloro-8-(3-fluoro-4-methylphenyl)-2-(trifluorom...)
Affinity DataIC50:  2.47E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336017(6-chloro-8-(4-isobutylphenyl)-2-(trifluoromethyl)-...)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336015(6-chloro-8-(4-ethoxyphenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336007(6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...)
Affinity DataIC50:  4.01E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336016(6-chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethy...)
Affinity DataIC50:  7.59E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50:  9.14E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336011(6-chloro-8-(4-fluorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336019(6-chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336010(8-(4-carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336007(6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336010(8-(4-carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed