Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50005821
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041376((R)-6-Ethyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041369((R)-10,13-Dimethyl-6-propyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041361((S)-6-Ethyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041371((S)-10,13-Dimethyl-6-vinyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041362((S)-6,10,13-Trimethyl-1,6,7,8,9,10,11,12,13,14,15,...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041366((S)-10,13-Dimethyl-6-propyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041365((R)-6-Butyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041367((R)-6-Benzyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataKi:  10nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041375((R)-6,10,13-Trimethyl-1,6,7,8,9,10,11,12,13,14,15,...)
Affinity DataKi:  11nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041372((S)-6-Butyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataKi:  12nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041370((R)-10,13-Dimethyl-6-phenyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataKi:  21nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041364((S)-6-Isopropyl-10,13-dimethyl-1,6,7,8,9,10,11,12,...)
Affinity DataKi:  22nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041363((R)-6-Isopropyl-10,13-dimethyl-1,6,7,8,9,10,11,12,...)
Affinity DataKi:  31nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041373((S)-10,13-Dimethyl-6-phenyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataKi:  37nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041368((S)-6-Ethynyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13...)
Affinity DataKi:  62nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041374((S)-6-Benzyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataKi:  63nMAssay Description:Binding affinity for human placental microsome aromatase Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041376((R)-6-Ethyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041369((R)-10,13-Dimethyl-6-propyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041361((S)-6-Ethyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataIC50:  260nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041371((S)-10,13-Dimethyl-6-vinyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataIC50:  320nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041362((S)-6,10,13-Trimethyl-1,6,7,8,9,10,11,12,13,14,15,...)
Affinity DataIC50:  350nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041366((S)-10,13-Dimethyl-6-propyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  390nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041365((R)-6-Butyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataIC50:  510nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041367((R)-6-Benzyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  660nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041375((R)-6,10,13-Trimethyl-1,6,7,8,9,10,11,12,13,14,15,...)
Affinity DataIC50:  720nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041372((S)-6-Butyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,1...)
Affinity DataIC50:  790nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041364((S)-6-Isopropyl-10,13-dimethyl-1,6,7,8,9,10,11,12,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041370((R)-10,13-Dimethyl-6-phenyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041363((R)-6-Isopropyl-10,13-dimethyl-1,6,7,8,9,10,11,12,...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041373((S)-10,13-Dimethyl-6-phenyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041368((S)-6-Ethynyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041374((S)-6-Benzyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed