Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50027802
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50247135(2-methyl-N-phenethyl-5-(phenylsulfonyl)benzenesulf...)
Affinity DataEC50:  3.88E+3nMAssay Description:Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50246651(CHEMBL474926 | N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-...)
Affinity DataEC50:  6.97E+3nMAssay Description:Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50247135(2-methyl-N-phenethyl-5-(phenylsulfonyl)benzenesulf...)
Affinity DataKd:  350nMAssay Description:Binding affinity to human sFRP1 by flurescence spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50246616(CHEMBL473916 | N-[3-(Dimethylamino)propyl]-2-ethyl...)
Affinity DataEC50:  1.27E+3nMAssay Description:Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50246617(2-Ethyl-5-(phenylsulfonyl)-N-(3-pyrrolidin-1-ylpro...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed