Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50035836
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  2.40nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  4.70nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012950(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  6.20nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012950(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  6.70nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of Cathepsin D from bovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPepsin A(Porcine)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50:  18nMAssay Description:Tested for inhibition of pepsin from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012952(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  110nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012952(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  270nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228479(CHEMBL3349575)
Affinity DataIC50:  1.50E+3nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50406108(CHEMBL2115235)
Affinity DataIC50:  2.10E+3nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012949(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  2.30E+3nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012949(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  2.50E+3nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50406108(CHEMBL2115235)
Affinity DataIC50:  3.50E+3nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50406109(CHEMBL2114246)
Affinity DataIC50:  4.20E+3nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50406109(CHEMBL2114246)
Affinity DataIC50:  4.20E+3nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228479(CHEMBL3349575)
Affinity DataIC50:  4.20E+3nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  8.00E+4nMAssay Description:Tested for inhibition of Cathepsin D from bovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50:  9.20E+4nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A(Porcine)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of pepsin from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of Angiotensin I converting enzyme from rabbit.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of Angiotensin I converting enzyme from rabbit.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of Chymotrypsinogen from bovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed