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Found 24 Enz. Inhib. hit(s) with all data for entry = 50042166
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095252((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  0.370nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095253((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  0.520nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095248((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  0.540nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095247((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  0.760nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095242((S)-3-[4-(3-Benzyl-2,5-dioxo-pyrrolidin-1-yl)-phen...)
Affinity DataIC50:  0.940nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095251((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  0.980nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095249((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  0.990nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095245((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  1.70nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095241((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  2.60nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095244((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  2.70nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095246((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  3.20nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095243((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  4.30nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095250((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  16nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095253((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  20nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095247((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  41nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095248((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  57nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095245((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  92nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095251((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  107nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095242((S)-3-[4-(3-Benzyl-2,5-dioxo-pyrrolidin-1-yl)-phen...)
Affinity DataIC50:  123nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095249((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  184nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095246((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  286nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095241((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  420nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095244((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  500nMAssay Description:Antagonistic activity against VLA-4 binding to recombinant human VCAM by ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50095243((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50:  650nMAssay Description:Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed