Compile Data Set for Download or QSAR
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Found 197 Enz. Inhib. hit(s) with all data for entry = 10907
TargetAdenosine receptor A2a(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577235(US11472811, Example 31B)
Affinity DataKi:  1.20nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM50202986(2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577292(US11472811, Example 76B)
Affinity DataKi:  1.60nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577283(US11472811, Example 69B)
Affinity DataKi:  1.60nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577300(US11472811, Example 82B)
Affinity DataKi:  1.70nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577256(US11472811, Example 48B)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577300(US11472811, Example 82B)
Affinity DataKi:  7.20nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577256(US11472811, Example 48B)
Affinity DataKi:  12nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577292(US11472811, Example 76B)
Affinity DataKi:  150nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577235(US11472811, Example 31B)
Affinity DataKi:  180nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM50202986(2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]...)
Affinity DataKi:  337nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577283(US11472811, Example 69B)
Affinity DataKi:  540nMAssay Description:Binding affinity of test compounds to four human adenosine receptors, A1, A2A, A2B and A3 was determined in radioligand competitive binding assay (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577220(US11472811, Example 18B)
Affinity DataIC50:  0.400nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577340((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  0.5nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577217(US11472811, Example 17B)
Affinity DataIC50:  0.600nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577339(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  0.600nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577336((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  0.700nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577196(US11472811, Example 1B)
Affinity DataIC50:  0.700nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577343((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  0.900nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577218(US11472811, Example 18)
Affinity DataIC50:  0.900nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577204(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  0.900nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577335(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577368((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  1nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577367((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  1.10nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577366(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.20nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577342((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  1.20nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577269(US11472811, Example 58B)
Affinity DataIC50:  1.30nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577231(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.30nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577194(US11472811, Example 1)
Affinity DataIC50:  1.40nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577224(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.40nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577227(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.5nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577205(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.5nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577256(US11472811, Example 48B)
Affinity DataIC50:  1.60nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577230(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.60nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577284(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.70nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577377((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  1.70nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577267(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.80nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577365(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.90nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577225(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.90nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577346(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  1.90nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577379((cis)-4-((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo...)
Affinity DataIC50:  2nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577354((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  2nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577206(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  2nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577370((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  2.10nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577348(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4...)
Affinity DataIC50:  2.20nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577202(US11472811, Example 4B)
Affinity DataIC50:  2.20nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577292(US11472811, Example 76B)
Affinity DataIC50:  2.20nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577239((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  2.30nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577235(US11472811, Example 31B)
Affinity DataIC50:  2.30nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577278((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  2.40nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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