Compile Data Set for Download or QSAR
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Found 11 Enz. Inhib. hit(s) with all data for entry = 50048124
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205347(CHEMBL3947950)
Affinity DataIC50:  2nMAssay Description:Inhibition of TrkA (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50142026(3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human N- terminal GST-tagged TrkA cytoplasmic domain (436 to 790 residues) expressed in baculovirus infected sf21 cells using biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205352(CHEMBL3962283)
Affinity DataIC50:  13nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced response measured after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205351(CHEMBL3977213)
Affinity DataIC50:  20nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205346(CHEMBL1576753)
Affinity DataIC50:  27nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205348(CHEMBL3934778)
Affinity DataIC50:  48nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced response measured after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205344(CHEMBL3934925)
Affinity DataIC50:  85nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205349(CHEMBL3901355)
Affinity DataIC50:  232nMAssay Description:Inhibition of human N- terminal GST-tagged TrkA cytoplasmic domain (436 to 790 residues) expressed in baculovirus infected sf21 cells using biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM67668((6E)-6-[4-(4-hydroxyanilino)-1H-quinazolin-2-ylide...)
Affinity DataIC50:  303nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205345(CHEMBL3964231)
Affinity DataIC50:  380nMAssay Description:Inhibition of human N- terminal GST-tagged TrkA cytoplasmic domain (436 to 790 residues) expressed in baculovirus infected sf21 cells using biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205350(CHEMBL391411)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of human N- terminal GST-tagged TrkA cytoplasmic domain (436 to 790 residues) expressed in baculovirus infected sf21 cells using biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed