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Found 4 Enz. Inhib. hit(s) with all data for entry = 50010693
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50:  47nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using positively supercoiled pBR322 DNA as substrate incubated for 25 mins by ethidium bromide stainin...More data for this Ligand-Target Pair
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50393503(CHEMBL2158050)
Affinity DataIC50:  300nMAssay Description:Inhibition of Staphylococcus aureus RN4220 DNA topoisomerase 4 expressed in Escherichia coli BL21(DE3) cells using supercoiled pBR322 DNA as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50393503(CHEMBL2158050)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Escherichia coli N-terminal His6-tagged DNA gyrase A expressed in Escherichia coli using relaxed pBR322 DNA as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50:  1.31E+6nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed