Found 11 Enz. Inhib. hit(s) with all data for entry = 50015879 
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP11 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins fol...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of N-terminal His-tagged human PARP15 catalytic domain expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 min...More data for this Ligand-Target Pair
