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Found 8 Enz. Inhib. hit(s) with all data for entry = 50015579
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50587662(CHEMBL1915474)
Affinity DataIC50:  0.978nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) incubated for 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 40 mins by intrinsic ATPase activity luminescence assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50587662(CHEMBL1915474)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of RAF1 (unknown origin) incubated for 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50587664(CHEMBL5181518)
Affinity DataIC50:  21nMAssay Description:Inhibition of human BRAF V600E mutant using MEK1 as substrate in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human BRAF V600E mutant using MEK1 as substrate in presence of ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50587663(CHEMBL5207384)
Affinity DataIC50:  35nMAssay Description:Inhibition of human BRAF V600E mutant using MEK1 as substrate in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562020(CHEMBL4798627)
Affinity DataIC50:  55nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 40 mins by intrinsic ATPase activity luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50587665(CHEMBL5173408)
Affinity DataIC50:  88nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 40 mins by intrinsic ATPase activity luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed