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maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50002231
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50133864(CHEMBL2139947 | US10251893, Compound 59)
Affinity DataIC50: <1nMAssay Description:Inhibition of porcupine in HEK293T cells transfected with Wnt3A-expressing vector assessed as suppression of Wnt/beta-catenin signaling after 22 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025020(CHEMBL3337854)
Affinity DataIC50:  22nMAssay Description:Inhibition of human CK1delta transcription variant 1 using GST-tagged mouse p53 (1 to 64 residues) as substrate in presence of radiolabelled-ATP by C...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428028(CHEMBL1257064)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025020(CHEMBL3337854)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat recombinant GST-tagged CK1delta using GST-tagged mouse p53 (1 to 64 residues) as substrate in presence of radiolabelled-ATP by Cher...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025020(CHEMBL3337854)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CK1delta transcription variant 2 using GST-tagged mouse p53 (1 to 64 residues) as substrate in presence of radiolabelled-ATP by C...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455468(CHEMBL1257114)
Affinity DataIC50:  60nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455466(CHEMBL4204681)
Affinity DataIC50:  90nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455466(CHEMBL4204681)
Affinity DataIC50:  90nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428027(CHEMBL1257090)
Affinity DataIC50:  140nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50365355(CHEMBL1257089)
Affinity DataIC50:  150nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428028(CHEMBL1257064)
Affinity DataIC50:  157nMAssay Description:Inhibition of porcupine in HEK293T cells transfected with Wnt3A-expressing vector assessed as suppression of Wnt/beta-catenin signaling after 22 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  210nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428035(CHEMBL2324266)
Affinity DataIC50:  210nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  230nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455467(CHEMBL4212803)
Affinity DataIC50:  270nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428028(CHEMBL1257064)
Affinity DataIC50:  320nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455473(CHEMBL4215433)
Affinity DataIC50:  330nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428035(CHEMBL2324266)
Affinity DataIC50:  400nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455466(CHEMBL4204681)
Affinity DataIC50:  410nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455468(CHEMBL1257114)
Affinity DataIC50:  420nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455467(CHEMBL4212803)
Affinity DataIC50:  520nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50365355(CHEMBL1257089)
Affinity DataIC50:  550nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455466(CHEMBL4204681)
Affinity DataIC50:  560nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428035(CHEMBL2324266)
Affinity DataIC50:  660nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455472(CHEMBL4209726)
Affinity DataIC50:  700nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455466(CHEMBL4204681)
Affinity DataIC50:  710nMAssay Description:Inhibition of porcupine in HEK293T cells transfected with Wnt3A-expressing vector assessed as suppression of Wnt/beta-catenin signaling after 22 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  760nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428028(CHEMBL1257064)
Affinity DataIC50:  930nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428027(CHEMBL1257090)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455471(CHEMBL4208290)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428027(CHEMBL1257090)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455467(CHEMBL4212803)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455467(CHEMBL4212803)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455468(CHEMBL1257114)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50365355(CHEMBL1257089)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428028(CHEMBL1257064)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428035(CHEMBL2324266)
Affinity DataIC50:  4.12E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50428027(CHEMBL1257090)
Affinity DataIC50:  7.07E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455468(CHEMBL1257114)
Affinity DataIC50:  7.34E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50365355(CHEMBL1257089)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455466(CHEMBL4204681)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of CK1delta in HEK293T cells assessed as stimulation of Wnt/beta-catenin signaling after 22 hrs in presence of Wnt3A-conditioned medium by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed