TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant ICMT (unknown origin) expressed in sf9 cells using biotin S-farnesyl-L-cysteine as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of SOS-mediated nucleotide release activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.42E+5nMAssay Description:Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of nucleotide exchange activityMore data for this Ligand-Target Pair