Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50015755
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105510(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-m...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160674(5-[4-(Benzenesulfonyl-methyl-amino)-3-methyl-3-phe...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104235(CHEMBL85086 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160678(5-[(R)-4-(Benzenesulfonyl-methyl-amino)-3-methyl-3...)
Affinity DataIC50:  3.60nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160682(CHEMBL180274 | N-Methyl-N-{(S)-2-methyl-4-[1-(4-ni...)
Affinity DataIC50:  5.30nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160679(CHEMBL426048 | N-Methyl-N-[(S)-2-methyl-2-phenyl-4...)
Affinity DataIC50:  6.40nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160683(5-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-methyl-3...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160675(CHEMBL361585 | N-[(S)-4-(1-Benzyl-2-oxo-octahydro-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160677(5-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-methyl-3...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160684(5-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-b...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160681(5-[4-(Benzenesulfonyl-methyl-amino)-3-methyl-3-phe...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160681(5-[4-(Benzenesulfonyl-methyl-amino)-3-methyl-3-phe...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160676(CHEMBL182188 | N-Methyl-N-[(S)-2-methyl-4-(1-methy...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160688(CHEMBL359752 | N-Methyl-N-{(S)-4-[4-((R)-2-oxo-5-p...)
Affinity DataIC50:  31.9nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160685(CHEMBL178337 | N-Methyl-N-{(S)-4-[4-((R)-4-methyl-...)
Affinity DataIC50:  36.7nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160686(CHEMBL178319 | N-Methyl-N-{(S)-4-[4-((S)-2-oxo-5-p...)
Affinity DataIC50: >100nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160680(CHEMBL359687 | N-Methyl-N-{(S)-4-[4-((R)-4-methyl-...)
Affinity DataIC50:  350nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160687(CHEMBL362637 | N-Methyl-N-[(S)-2-methyl-4-(octahyd...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160674(5-[4-(Benzenesulfonyl-methyl-amino)-3-methyl-3-phe...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHOcells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed