Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50020507
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214682(1-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trifluorome...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214688(1-{4-[(1R)-2-(amino-3-methylbutyl)-6-fluorophenyl]...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214704(1-{4-[(1S)-2-(amino-3-methylbutyl)-4-fluorophenyl]...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214695(1-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trifluorome...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214689(1-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trifluorome...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214703(1-{4-[(1R)-2-(amino-3-methylbutyl)-6-fluorophenyl]...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214679(1-{4-[(1S)-2-(amino-3-methylbutyl)-6-trifluorometh...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214691(1-{4-[(1S)-2-(1-amino-3-methylbutyl)-6-trifluorome...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214700(1-{4-[(1S)-2-(1-amino-3-methylbutyl)-6-fluoropheny...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214696(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trif...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214681(1-[(R)-2-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trif...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214685(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to C57BL/6J mouse MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214692(1-{4-[(1R)-2-(1-amino-3-methylbutyl)-6-fluoropheny...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214701(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)phenyl)p...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214698(1-{4-[(1R)-2-(1-amino-3-methylbutyl)-6-fluoropheny...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214684(1-{4-[(1S)-2-(1-amino-3-methylbutyl)-6-fluoropheny...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214699(1-[(S)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214685(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataKi:  9.10nMAssay Description:Binding affinity to rat MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214697((1S)-(2-{4-[(2R)-(2-oxo-1-pyrrolidinyl)-3-(2,4-dic...)
Affinity DataKi:  9.70nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214702(1-{4-[(1R)-2-(amino-3-methylbutyl)-4-fluorophenyl]...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214685(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214686(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluor...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214680(1-{4-[(1R)-2-(1-amino-3-methylbutyl)-4-fluoropheny...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214683(1-{4-[(1R)-2-(amino-3-methylbutyl)-6-trifluorometh...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214687(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)phenyl]-...)
Affinity DataKi:  38nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214694((R)-2-amino-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-...)
Affinity DataKi:  39nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214693(1-{4-[(1R)-2-(1-amino-3-methylbutyl)-6-trifluorome...)
Affinity DataKi:  47nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214690(2-amino-N-((R)-1-(4-(2-((R)-1-amino-3-methylbutyl)...)
Affinity DataKi:  49nMAssay Description:Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214688(1-{4-[(1R)-2-(amino-3-methylbutyl)-6-fluorophenyl]...)
Affinity DataKi:  240nMAssay Description:Displacement of [125I]NDP-MSH from MC5R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214696(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trif...)
Affinity DataKi:  250nMAssay Description:Displacement of [125I]NDP-MSH from MC5R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214681(1-[(R)-2-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trif...)
Affinity DataKi:  360nMAssay Description:Displacement of [125I]NDP-MSH from MC5R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214688(1-{4-[(1R)-2-(amino-3-methylbutyl)-6-fluorophenyl]...)
Affinity DataKi:  450nMAssay Description:Displacement of [125I]NDP-MSH from MC3R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214696(1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trif...)
Affinity DataKi:  640nMAssay Description:Displacement of [125I]NDP-MSH from MC3R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214681(1-[(R)-2-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trif...)
Affinity DataKi:  950nMAssay Description:Displacement of [125I]NDP-MSH from MC3R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214685(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataKi:  990nMAssay Description:Displacement of [125I]NDP-MSH from MC5R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214685(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [125I]NDP-MSH from MC3R receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214681(1-[(R)-2-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trif...)
Affinity DataIC50:  210nMAssay Description:Agonist activity at human MC4 receptor in HEK293 cells assesed as inhibition of alpha-MSH stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214685(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataIC50:  510nMAssay Description:Agonist activity at human MC4 receptor in HEK293 cells assesed as inhibition of alpha-MSH stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50214685(1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifl...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at ghrelin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed