Found 32 Enz. Inhib. hit(s) with all data for entry = 50015020 
Affinity DataIC50: 4nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
3D Structure (crystal)TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 197nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 313nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 596nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 861nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 952nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.74E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.77E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 4.95E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
