Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50030275
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293568(CHEMBL563761 | Cis-N-(3-Chlorobenzyl)-N-(-4-aminoc...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293558(1-Methyl-1H-imidazole-4-carboxylic acid(3-ethyl-3-...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293559(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopro...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293560(1-Methyl-1H-imidazole-4-carboxylic acid(3-methyl-3...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293557((R)-N[3-phenyl-3-(4'-(4-toluoyl)phenoxy)-propyl]sa...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293561(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopen...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293562(1-Methyl-1H-imidazole-4-carboxylic acid(3-chloro-b...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293563(1-Methyl-1H-imidazole-4-carboxylic acid(3-chloro-b...)
Affinity DataKi:  11nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293564(1-Methyl-1H-imidazole-4-carboxylic acid(3-chloro-4...)
Affinity DataKi:  12nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293565(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataKi:  15nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293566(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataKi:  95nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293567(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataKi:  109nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203572((1-(4-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  27nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293561(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopen...)
Affinity DataIC50:  460nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293559(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopro...)
Affinity DataIC50:  530nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293568(CHEMBL563761 | Cis-N-(3-Chlorobenzyl)-N-(-4-aminoc...)
Affinity DataIC50:  1.15E+3nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293558(1-Methyl-1H-imidazole-4-carboxylic acid(3-ethyl-3-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293560(1-Methyl-1H-imidazole-4-carboxylic acid(3-methyl-3...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293564(1-Methyl-1H-imidazole-4-carboxylic acid(3-chloro-4...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293561(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293560(1-Methyl-1H-imidazole-4-carboxylic acid(3-methyl-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293558(1-Methyl-1H-imidazole-4-carboxylic acid(3-ethyl-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293564(1-Methyl-1H-imidazole-4-carboxylic acid(3-chloro-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293565(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293567(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293559(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293562(1-Methyl-1H-imidazole-4-carboxylic acid(3-chloro-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293563(1-Methyl-1H-imidazole-4-carboxylic acid(3-chloro-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293557((R)-N[3-phenyl-3-(4'-(4-toluoyl)phenoxy)-propyl]sa...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293567(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293568(CHEMBL563761 | Cis-N-(3-Chlorobenzyl)-N-(-4-aminoc...)
Affinity DataIC50:  6.56E+4nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed