Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 2865
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25494(4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25495(4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25493(4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-y...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25492(4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25496(4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-y...)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25498(4-(4-chloro-2-fluorophenyl)-N-(6-fluoro-1H-indazol...)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25483(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25500(4-(4-chloro-2-fluorophenyl)-N-(6-fluoro-1H-indazol...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25499(4-(4-chloro-2-fluorophenyl)-2-(2-ethoxypyridin-4-y...)
Affinity DataIC50:  11nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM14048(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  14nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25497(4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-y...)
Affinity DataIC50:  15nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25491(4-[2-fluoro-4-(trifluoromethyl)phenyl]-N-(1H-indaz...)
Affinity DataIC50:  26nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25478(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-2-(4-methox...)
Affinity DataIC50:  46nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25490(Dihydropyrimidine, 19 | N-(1H-indazol-5-yl)-2-(4-m...)
Affinity DataIC50:  68nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25487(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  75nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25479(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  101nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25480(2-(3-fluoro-4-methylphenyl)-4-(4-fluorophenyl)-N-(...)
Affinity DataIC50:  104nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25484(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  105nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25477(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  105nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25482(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  129nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25481(2-(4-chlorophenyl)-4-(4-fluorophenyl)-N-(1H-indazo...)
Affinity DataIC50:  129nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25488(Dihydropyrimidine, 17 | N-(1H-indazol-5-yl)-4-(4-m...)
Affinity DataIC50:  150nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25486(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  180nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25485(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50:  288nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25489(Dihydropyrimidine, 18 | N-(1H-indazol-5-yl)-2-(4-m...)
Affinity DataIC50:  863nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed