Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 217
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228249(1-(3-hydroxycyclohexyl)-3-methyl-8-(6-(1-methyl-1H...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228242(8-(6-aminopyridin-3-yl)1-((1s,4s)-4-hydroxycyclohe...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228247((S)-3-methyl-1-(1-(methanesulfonyl)pyrrolidin-3-yl...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228246((S)-1-(1-(ethylsulfonyl)pyrrolidin-3-yl)-3-methyl-...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228245((S)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridi...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228250(N-((1s,4s)-4-(3-methyl-8-(6-(1-methyl-1H-pyrazol-4...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228245((S)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridi...)
Affinity DataIC50: <10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228243((R)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridi...)
Affinity DataIC50: <10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228204(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50: <10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228257((S)-3-methyl-1-(1-(methanesulfonyl)pyrrolidin-3-yl...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228256((S)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridi...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228255(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228204(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228253((1s,4s)-4-(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228251(N-((1s,4s)-4-(3-methyl-8-(6-(1-methyl-1H-pyrazol-4...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228223(1-((1r,4r)-4-hydroxycyclohexyl)-3-methyl-8-(6-(1-m...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228226(1-((1s,4s)-4-hydroxycyclohexyl)-3-methyl-8-(6-(1-m...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228227(1-((1s,4s)-4-hydroxycyclohexyl)-3-methyl-8-(6-phen...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228204(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228248((R)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridi...)
Affinity DataIC50: <10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228206(1-(1-((R)-2-hydroxypropionyl)piperidin-3-yl)-3-met...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228226(1-((1s,4s)-4-hydroxycyclohexyl)-3-methyl-8-(6-(1-m...)
Affinity DataIC50: <10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228207(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228248((R)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridi...)
Affinity DataIC50: <10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228236(1-((1r,4r)-4-hydroxycyclohexyl)-3-methyl-8-(6-phen...)
Affinity DataIC50:  25nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228235(1-((1r,4r)-4-hydroxycyclohexyl)-8-(6-methoxyl-5-me...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228233(1-((1s,4s)-4-hydroxycyclohexyl)-3-methyl-8-(6-meth...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228232(1-((1s,4s)-4-hydroxycyclohexyl)-3-methyl-8-(1-phen...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228229(1-((1s,4s)-4-hydroxycyclohexyl)-8-(6-methoxyl-5-me...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228205(1-(1-((S)-2-hydroxypropionyl)piperidin-3-yl)-3-met...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228200(1-(1-(2-hydroxyacetyl)piperidin-3-yl)-3-methyl-8-(...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228234(1-((1r,4r)-4-hydroxycyclohexyl)-3-methyl-8-(1-phen...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228222(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228221(3-(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228220(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228217(1-(1-((4-chlorphenyl)sulfonyl)pyrrolidin-3-yl)-3-m...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228216(1-(1-benzylpyrrolidin-3-yl)-3-methyl-8-(6-(1-methy...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228243((R)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridi...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228212(1-(1-ethylpyrrolidin-3-yl)-3-methyl-8-(6-(1-methyl...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228210(3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228209(1-(1-(2-hydroxyacetyl)pyrrolidin-3-yl)-3-methyl-8-...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228203(1-(1-(1H-1,2,4-triazole-3-carbonyl)piperidin-3-yl)...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228215(1-(1-acetylpyrrolidin-3-yl)-3-methyl-8-(6-(1-methy...)
Affinity DataIC50:  550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent