Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50001080
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006687((S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012504(2-{5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006691((S)-2-(4-(methyl((2-methyl-4-oxo-3,4-dihydroquinaz...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)
Affinity DataIC50:  670nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012514(2-{5-[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  720nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012517(2-(4-{1-[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinaz...)
Affinity DataIC50:  1.07E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012520(2-(4-{[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  2.62E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012506(2-{[1-(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataIC50:  3.27E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012515(2-[(5-{[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazo...)
Affinity DataIC50:  3.82E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012525(2-{4-[1-(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-y...)
Affinity DataIC50:  4.30E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012516((S)-2-(4-((2-methyl-4-oxo-3,4-dihydroquinazolin-6-...)
Affinity DataIC50:  4.50E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012526(2-[4-(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50:  4.66E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012507(2-{3-Fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazo...)
Affinity DataIC50:  6.73E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012513(2-({5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  6.98E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012521(2-{5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataIC50:  8.27E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012508(2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yla...)
Affinity DataIC50:  8.28E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012509(2-[(5-{[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  8.42E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012510(2-(4-{[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  9.52E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012522(2-[(5-{[(2-Fluoro-ethyl)-(2-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  9.90E+3nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012505(2-[4-(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylsu...)
Affinity DataIC50:  1.03E+4nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012518(2-[(5-{[(2-Hydroxy-ethyl)-(2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50:  1.33E+4nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012512(2-[(5-{[Allyl-(2-methyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  1.41E+4nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012519(2-({6-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  1.67E+4nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012523(2-[4-(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50:  2.15E+4nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012524((S)-2-(5-((2-methyl-4-oxo-3,4-dihydroquinazolin-6-...)
Affinity DataIC50:  2.48E+4nMAssay Description:In vitro inhibition of the compound against L1210 thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed