Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 6548
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM82190(Salicylic acid derivative, compound 2)
Affinity DataIC50:  7.00E+3nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM138386(US8877791, B1)
Affinity DataIC50:  1.00E+4nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM50261993(5-(methylthio)thiophene-2-carboxylic acid | CHEMBL...)
Affinity DataIC50:  1.00E+4nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM138387(US8877791, D1)
Affinity DataIC50:  2.00E+4nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM138388(US8877791, G1)
Affinity DataIC50:  7.00E+4nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM138389(US8877791, H1)
Affinity DataIC50:  9.00E+4nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM138385(US8877791, A1)
Affinity DataIC50:  9.00E+4nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPyruvate kinase PKM(Homo sapiens (Human))
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM11995(2-chloro-5-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic ac...)
Affinity DataIC50: >1.00E+5nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
In DepthDetails US Patent