Compile Data Set for Download or QSAR
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Found 45 Enz. Inhib. hit(s) with all data for entry = 50031605
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  9nMAssay Description:Binding affinity to human recombinant LXRbeta ligand binding domainMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316094(3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(tr...)
Affinity DataIC50:  18nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316092(5-Chloro-3-methyl-2-[3'-(methylsulfonyl)biphenyl-4...)
Affinity DataIC50:  34nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316097(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataIC50:  53nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305494(4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  61nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316096(CHEMBL1090916 | N-Methyl-4'-[3-methyl-5-(trifluoro...)
Affinity DataIC50:  81nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316102(2-[3'-(Ethylsulfonyl)biphenyl-4-yl]-3-methyl-5-(tr...)
Affinity DataIC50:  132nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316094(3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(tr...)
Affinity DataIC50:  165nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316091(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]quino...)
Affinity DataIC50:  299nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316090(5-Methoxy-3-methyl-2-[3'-(methylsulfonyl)biphenyl-...)
Affinity DataIC50:  395nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316092(5-Chloro-3-methyl-2-[3'-(methylsulfonyl)biphenyl-4...)
Affinity DataIC50:  734nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316098(3-Methyl-2-[4'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316099(3-Methyl-2-[2'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316098(3-Methyl-2-[4'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316097(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316100(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-3-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316099(3-Methyl-2-[2'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316101(3-Methyl-2-[4'-(methylsulfonyl)biphenyl-3-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316100(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-3-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316101(3-Methyl-2-[4'-(methylsulfonyl)biphenyl-3-yl]-5-(t...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316102(2-[3'-(Ethylsulfonyl)biphenyl-4-yl]-3-methyl-5-(tr...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316096(CHEMBL1090916 | N-Methyl-4'-[3-methyl-5-(trifluoro...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316095(CHEMBL1089231 | N-Methyl-4'-[3-methyl-5-(trifluoro...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316093(2-[3'-(Methylsulfonyl)biphenyl-4-yl]-5-(trifluorom...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316093(2-[3'-(Methylsulfonyl)biphenyl-4-yl]-5-(trifluorom...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316095(CHEMBL1089231 | N-Methyl-4'-[3-methyl-5-(trifluoro...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316091(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]quino...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316090(5-Methoxy-3-methyl-2-[3'-(methylsulfonyl)biphenyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305494(4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  1.77E+3nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316097(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human LXRbeta in HEK293 cells assessed as Gal4 transactivationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316097(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316097(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant LXRalpha ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305494(4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataEC50:  5.10E+3nMAssay Description:Agonist activity at human recombinant LXRalpha ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human LXRbeta in HEK293 cells assessed as Gal4 transactivationMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316094(3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(tr...)
Affinity DataEC50:  2.02E+3nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316092(5-Chloro-3-methyl-2-[3'-(methylsulfonyl)biphenyl-4...)
Affinity DataEC50:  860nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  53nMAssay Description:Agonist activity at human LXRalpha in HEK293 cells assessed as Gal4 transactivationMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316094(3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(tr...)
Affinity DataEC50:  3.59E+3nMAssay Description:Agonist activity at human recombinant LXRalpha ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305494(4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305494(4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human LXRbeta in HEK293 cells assessed as Gal4 transactivationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305494(4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataEC50:  1.09E+4nMAssay Description:Agonist activity at human LXRalpha in HEK293 cells assessed as Gal4 transactivationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human recombinant LXRalpha ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316097(3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(t...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human LXRalpha in HEK293 cells assessed as Gal4 transactivationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed